Dietary Supplements Flashcards
what does the FDA look at before approving a drug to be available on the market?
safety
efficacy
quality control
true/false: no review/approval is required by the FDA for supplements before they can be available on the market
true
what does the dietary supplement health and education act (1994) do?
defines dietary supplements
new framework for safety
guidelines for literature displayed
claims and nutritional support statements
ingredient and nutrition labeling
granted FDA authority to establish good manufacturing practice regulations
what does the FDA have the power to do with supplements?
can take action after is on the market if it is unsafe
are health claims allowed on veterinary products?
no
what do human health claims require?
pre-approval: significant scientific agreement, qualified health claims
what are some issues in the use of dietary supplements?
efficacy
dose
safety
quality control
pharmacological properties
why is dose an issue with dietary supplements?
appropriate dose often not established in people, rarely in companion animals
what does the national animal supplement council do?
provides seal: can buy, not a lot of rigor goes into
what is a company that provides a human supplement seal that is actually indicative of quality control?
USP dietary supplements verification program for human dietary supplements
what are the potential beneficial effects of omega-3 fatty acids?
reduce inflammatory eicosanoids
reduce inflammatory cytokines
anti-neoplastic effects
correct deficiency
reduce arrhythmogenesis
what are some adverse effects of omega-3 fatty acids?
coagulopathies: effects on platelets
toxicity
what should you think about with omega-3 fatty acids supplementation?
use fish oil
quality control is important
avoid cod liver oil
avoid flax seed/flax seed oil
what are the potential adverse effects of glucosamine/chondroitin?
general: gastrointestinal
quality control issues
glucosamine: amino sugar, glucose regulation?
chondroitin-sulfate: coagulation effects?
