Antiprotozoals Flashcards
what are some coccidiocides?
sulfonamides: primarily sulfadimethoxine (albon) or sulfaquinoxaline
what are some coccidiostats?
ionophores: cattle, poultry, small ruminants
what is the primary toxicity of ionophore toxicity?
severe muscle damage, including cardiac muscle
who is the most sensitive to ionophore toxicity?
horses
who is relatively resistant to ionophore toxicity?
cattle and poultry
what is a coccidiostat used for extra-label use in puppies and kittens?
ponazuril (marquis)
what drugs are used to treat toxoplasmosis?
clindamycin
pyrimethamine + sulfadiazine (or TMS)
what are the treatments for equine protozoal myelitis?
pyrimethamine + sulfadiazine (ReBalance)
ponazuril (marquis)
diclazuril (protazil)
what drugs are used to treat giardiasis?
fenbendazole
metronidazole
can we use nitroimidazoles extralabelly in food animals?
no
what is ronidazole used for?
cats with trichomonad diarrhea
unapproved, must be compounded
what is used to treat babesiosis?
imidocarb diproprionate: carbamate, potential for cholinergic side effects: consider atropine pretreatment
______________, a human anti-malarial drug, and ______________, has been shown to eliminate the carrier state for Babesia gibsoni
atovaquone
azithromycin
what is the treatment for canine hepatozoonosis?
simultaneous use of the following:
potentiated sulfonamide
clindamycin
pyrimethamine
how can we treat H. canis?
imidocarb can clear parasitemia
