Deck 7

Question 1

The role of corticosteroids is to influence the activity of:

Answer 1

NF-kB as well as other transcription factors resulting in suppression of expression of different genes in activated T cells or macrophages

Question 2

Type III hypersensitivity reaction is mediated by:

Answer 2

Complement activation by immune complexes deposited in the blood vessel walls, kidneys and joints.

Question 3

Cytokines with anti-inflammatory activity are:

Answer 3

IL-10 and TGF-a

Question 4

Intradermal skin (prick) test is used for the diagnosis of diseases caused by hypersensitivity type:

Answer 4

I

Question 5

The immunoglobulin isotope is determined by the:

Answer 5

H chain constant region

Question 6

Give examples of innate immune responses:

Answer 6

Macrophages release chemokine to attract neutrophils to the site of inflammation

Complement activated on a bacterial membrane releases inflammatory chemoattractants

Question 7

Give example of adaptive immune response:

Answer 7

IgA block the adhesion of E. coli to interstitial epithelial cells

Question 8

The term ‘‘antigenic mimicry’’ refers to:

Answer 8

Structural similarity of microbial antigens to body molecules

Question 9

Secondary (peripheral) lymphoid organs are:

Answer 9

Spleen, lymph nodes and MALT

Question 10

A positive skin reaction to bovine tuberculin means that one has:

Answer 10

Memory Th1 cells specific for mycobacterium bovis

Question 11

Gene recombination is a biological mechanism that results:

Answer 11

The random formation of TCR or BCR

Question 12

Interferons inhibit:

Answer 12

virus replication by infected cells

Question 13

The chemotactic effect has:

Answer 13

C3b, C5a and C5b67

Question 14

Antibody binding to antigen does NOT lead to:

Answer 14

direct killing of the living cells

Question 15

The ligand for TCR:

Answer 15

MHC molecules with antigenic peptide

Question 16

A fundamental difference between the antigen receptor on B cells (BCR) and on T cells is that they have:

Answer 16

Different requirements for antigen presentation

Question 17

Neutrophil migration to the site of inflammation is affected by:

Answer 17

C3a or C3b
N-formulated methionine-containing peptides
IL-8

Question 18

Professional phagocytes are:

Answer 18

Macrophages and neutrophils

Question 19

Lysosome break down:

Answer 19

excess or worn-out cell parts

Question 20

Lysosome splits:

Answer 20

peptidoglycan