Deck 5 Flashcards

1
Q

Antigenicity means the ability of a substance:

A

To bind specific antibodies

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2
Q

Antibodies in defence against extracellular pathogens are NOT required for:

A

direct killing of invaders

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3
Q

By skin test in cattle with bovine tuberculin is tested the presence of:

A

Memory Th1 lymphocytes specific for mycobacterium bovis

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4
Q

Ileal Peyer’s patches is for:

A

development of mature B cells in Ru, dogs and swine

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5
Q

Spleen is for:

A

blood filtration and trapping of antigen from blood

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6
Q

Thymus is for:

A

development of mature T cells

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7
Q

IL-1 is produced by macrophages and acts on the hypothalamus to induce fever. This is an example of:

A

endocrine action

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8
Q

Anti-inflammatory action of corticosteroids is given by inhibition of:

A

phospholipase A
NF-kB

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9
Q

Superantigens:

A

Non-specifically bind to MHC class II molecule on antigen presenting cells and to TCR on T helper cells
Cause non-specific activation of T-cells, resulting in polyclonal T cell activation and massive cytokine production

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10
Q

The anaphylatoxic effect has:

A

C5a and C3a

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11
Q

Killing of virus by NK cells is or is not an antiviral mechanism used by the immune system?

A

Is NOT

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12
Q

Antiviral mechanisms used by the immune system include:

A

IFN activation of virus-infected cells
Lysis of virus by complement
Lysis of virus-infected cells by complement

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13
Q

The primary purpose of the adaptive immune system is to:

A

Protect from disease upon re-infection with a specific pathogen

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14
Q

Coombs test is used for the diagnostic of disease caused by hypersensitivity:

A

type II

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15
Q

Positive selection of T-lymphocytes ensures that the T-lymphocytes recognise:

A

Self-MHC molecules survive

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16
Q

Immunoglobulin class switching is a biological mechanism that:

A

Changes a B-cell production of antibodies from one class to another

17
Q

NK cells are activated after:

A

Binding of ligand to KAR receptors in the abscence of activated KIR receptors

18
Q

Toxoid vaccines contain chemically modified:

A

bacterial toxins (products)

19
Q

Signalling to a cytotoxic T cell that a cell is infected with virus depends on:

A

binding of processed antigen to cell class I MHC

20
Q

To make a recombinant vaccine to a virus, the virus DNA is expressed:

A

In an avirulent vector, which may be a virus or a bacterium

21
Q
A