Deck 10

Question 1

What is a DIVA vaccine?

Answer 1

DIVA = differentiation of infected from vaccinated animals
Marker vaccine to allow for immunological differentiation

Question 2

Class IgM antibodies are secreted as:

Answer 2

pentamers

Question 3

Which multimeric Ig has a secretory component?

Answer 3

IgA

Question 4

Which multimeric Ig(s) has a J chain?

Answer 4

IgM and IgA

Question 5

During the activation of macrophages, the formation of toxic NO radicals also occurs due to the activation of:

Answer 5

NOS, which catalyzes the formation of nitrogen oxide from arginine

Question 6

Examples of MAMPs (microbe associated molecular patterns):

Answer 6

Flagellin
Eukaryotic DNA
Peptidoglycan

Question 7

Cytokines that regulate cell migration are called:

Answer 7

chemokines

Question 8

Two reasons for chronic inflammation:

Answer 8

Autoimmune diseases or prolonged immune responses

Question 9

C3 convertase of the alternative complement pathway:

Answer 9

C3bBb

Question 10

TCR forms a complex with:

Answer 10

CD3

Question 11

Helper T lymphocytes are characterised by the presence of:

Answer 11

CD4 antigen

Question 12

Cytotoxic T lymphocytes are characterized by the presence of:

Answer 12

CD8 antigen

Question 13

What is the valence of the antibody?

Answer 13

Number of antigenic determinants that an individual antibody molecule can bind

Question 14

If cytokine has a different effect on different types of target cells, then this cytokine has:

Answer 14

pleiotrophic effect

Question 15

Presence of memory cells demonstrate:

Answer 15

immune memory

Question 16

An example of acquired immunity is:

Answer 16

recognition and killing of virus infected cells by cytotoxic T cells

Question 17

An example of innate immunity is:

Answer 17

recognition and killing of cancer cells by NK cells

Question 18

Lymphocytes are, according the morphology of their nucleus:

Answer 18

mononuclear leukocytes

Question 19

The digestion of the phagocytosed particle takes place in a formation called:

Answer 19

phagosome or phagolysosome

Question 20

Somatic hypermutation is mediated by a B-cell enzyme called:

Answer 20

AID: activation-induced cytosine deaminase

Question 21

ADCC is a process in which antibody-coated cells are killed by:

Answer 21

NK cells