Deck 13 Flashcards
What is a haptoglobin?
A substance that reduces oxidative damage associated with haemolysis by binding free haemoglobin. It also has bacteriostatic and immunomodulatory effects.
Cytokines that play an important role in the development of chronic inflammatory response are:
IL-1
TNF-a
IL-6
IL-12
IL-4
IL-10
TGF-b
Somatic hypermutation is:
a cellular mechanism by which the immune system adapts to the new foreign elements that confront it, as seen during class switching
The result of somatic hypermutation is:
B cells that emerge gets a stronger and more specific response to the antigen (affinity maturation), by enhancing the diversity of their BCR repertoire
When cytokines react to cells close to them this is an example of:
paracrine action