Deck 2

Question 1

An advantage of giving passive immunization is that it provides:

Answer 1

faster immunity

Question 2

Isotype switching or class switching changes:

Answer 2

only the isotype of secreted antibody (e.g., IgM to IgG)

Question 3

Adaptive cell-mediated immunity involves the generation of activated antigen-specific effector:

Answer 3

T cells

Question 4

What is the characteristic that best defines the acquired immune response?

Answer 4

It exhibits immunological memory

Question 5

Depot adjuvant is used:

Answer 5

To slow down antigen release

Question 6

Immunoglobulin isotype is determined by:

Answer 6

H-chain constant region

Question 7

Cytokines with anti-inflammatory activity are:

Answer 7

IL-10 and TGF-a

Question 8

Somatic hypermutation is a biological mechanism that:

Answer 8

increases specificity of antibodies produced by plasma cells

Question 9

Endogenous antigen presentation require delivery of antigen peptides to the ER by:

Answer 9

TAP molecules

Question 10

The ability of an antigen to induce an immune response does not depend on the antigens:

Answer 10

Ability to enter the thyroid

Question 11

Th2 cells secrete cytokines which:

Answer 11

Stimulate production of B cells

Question 12

Facultative intracellular bacteria can survive in phagocytes due to their ability to:

Answer 12

Inhibit fusion of phagosome with lysosome

Question 13

Major role of helper T cell is:

Answer 13

production of cytokines

Question 14

The primary purpose of the adaptive immune system is to:

Answer 14

protect from disease upon re-infection with a specific pathogen

Question 15

A ligand is:

Answer 15

An enzyme
A cytokine
Antigen
or molecule that specifically binds a receptor

Question 16

Effector function of complement does NOT include:

Answer 16

presentation of antigen to B cell

Question 17

A mature lymphocyte which has specific antigen receptors but cannot respond to that antigen is called:

Answer 17

Anergic

Question 18

Early induced immune responses are like adaptive immunity in that they:

Answer 18

involve macrophages and complement

Question 19

IgA can be secreted from the body because it:

Answer 19

Binds poly-Ig receptor on mucosal epithelial cells

Question 20

T cell moves from the circulation into the periphery lymphoid tissues when they bind:

Answer 20

vascular addressins