CVS: The Cardiac Cycle Flashcards

1
Q

Define systole.

A

Contraction and rejection of blood from the ventricles.

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2
Q

Define diastole.

A

Relaxation and fill of the ventricles.

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3
Q

Where is the tricuspid valve?

A

Right side, between the atria and the ventricles

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4
Q

Where is the mitral value found?

A

The left side, between the atria and the ventricles.

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5
Q

Where is the pulmonary valve found?

A

The entrance of the pulmonary artery

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6
Q

Where is the aortic valve found?

A

The entrance if the aorta

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7
Q

Which is under higher pressure, the systemic circulation or pulmonary circulation?

A

Systemic

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8
Q

What is stroke volume?

A

The amount of blood each ventricle ejects each beat.

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9
Q

What is the average stroke volume?

A

70ml blood per beat

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10
Q

What is relatively different about a cardiac action potential?

A

It’s relatively long, approx 280ms

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11
Q

What anatomical structure prevents inversion of valves on systole?

A

Attachments called chordae tendinease, which attach the valves to papillary muscles.

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12
Q

Name the 7 stages of the cardiac cycle.

A
  1. Atrial Contraction
  2. Isovolumetric Contraction
  3. Rapid Ejection
  4. Reduced Ejection
  5. Isovolumetric Relaxation
  6. Rapid Filling
  7. Reduced Filling
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13
Q

Describe the relative timings of systole and diastole.

A

Diastole approx 0.55s
Systole approx 0.35s

(At 67 BPM)

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14
Q

How do the relative timings of systole and diastole change during exercise?

A

Systole remains the same, diastole increases in speed

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15
Q

What is the origin of S1?

A

The closing of tricuspid valve and the mitral valve.

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16
Q

What is the origin of S2?

A

The closing of the aortic and pulmonary valves

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17
Q

What is the Wiggers diagram?

A

Compares changes in pressure with changes in volume, changes in electrochemical properties and with the sounds of the heart

18
Q

Which side if the heart do wiggers diagrams usually plot? What would be the different if the other side of the heart was to be plotted?

A
  • Left

- Right would be the same but at a lower pressure

19
Q

In a wiggers diagram, what is one heart beat equivalent to?

A

One systole and one diastole

20
Q

What position are the valves in during atrial contraction?

A

Mitral/ Tricuspid: Open

Aortic/ Pulmonary: Closed

21
Q

What position are the valves in during Isovolumetric contraction?

A

Mitral/ Tricuspid: Closed

Aortic/ Pulmonary: Closed

22
Q

What position are the valves in during Rapid Ejection?

A

Mitral/ Tricuspid: Closed

Aortic/ Pulmonary: Open

23
Q

What position are the valves in during Reduced Ejection?

A

Mitral/ Tricuspid: Closed

Aortic/ Pulmonary: Open

24
Q

What position are the valves in during Isometric Relaxation?

A

Mitral/ Tricuspid: Closed

Aortic/ Pulmonary: Closed

25
Q

What position are the valves in during Rapid Filling?

A

Mitral/ Tricuspid: Open

Aortic/ Pulmonary: Closed

26
Q

What position are the valves in during Reduced Ejection?

A

Mitral/ Tricuspid: Open

Aortic/ Pulmonary: Closed

27
Q

What are the 2 types of left valve abnormalities?

A
  1. Stenosis

2. Regurgitation

28
Q

What is a stenosis?

A

When the valve doesn’t open enough

29
Q

What is regurgitation?

A

Valve doesn’t close all the way

30
Q

How does Aortic valve regurgitation affect the function of the heart?

A
  • Blood flows back into LV during diastole. This increases the stroke volume hence systolic pressure increases and diastolic pressure decreases. This results in a bounding pulse leading to head bobbing or Quinke’s sign.
  • LV hypertrophy
31
Q

How does Aortic valve stenosis affect the function of the heart?

A
  • Increased LV pressure -> LV hypertrophy

- Left sided heart failure -> syncope (fainting) and angina

32
Q

How does mitral valve regurgitation affect the function of the heart?

A

Increases preload causing LV hypertrophy

33
Q

How does mitral valve stenosis affect the function of the heart?

A
  • Increase in LA pressure
  • Pulmonary oedema ->RV hypertrophy
  • LA dilation -> atrial fibrillation or oesophagus compression
34
Q

How will aortic stenosis affect the heart sounds?

A

Crescendo-decrescendo murmur

35
Q

How will aortic valve regurgitation affect the heart sounds?

A

Early decrescendo diastolic murmur

36
Q

How will mitral valve stenosis affect the heart sounds?

A

Snap as valve opens: diastolic rumble

37
Q

How will mitral valve regurgitation affect the heart sounds?

A

Holosystolic mumber

38
Q

Define afterload.

A

The load the heart must eject blood against (roughly equivalent to aortic pressure)

39
Q

Define preload.

A

Amount the ventricles stretched in diastole

40
Q

Define total peripheral resistance.

A

Resistance to blood flow offered by all systemic vasculature

41
Q

Which vessels offer the greatest resistance?

A

Arterioles

42
Q

State the frank-Starling law.

A

The more the heart fills the harder it contracts (up to a limit)