CV - nitrates Flashcards
1
Q
organic nitrate drugs
A
nitroglycerin [NTG]
-SL pill, patch, paste, spray
isosorbide
-PO pill
2
Q
nitroglycerin + isosorbide [nitrates]
MOA
A
dilates veins + decrease venous returns to right side of heart
3
Q
nitroglycerin + isosorbide [nitrates]
Tx
A
angina
prevents or reduces coronary artery spasm
reduce cardiac oxygen deman
4
Q
nitroglycerin + isosorbide [nitrates]
AE
A
- headache
- bitter taste
- OH
- reflex tachycardia
- tolerance/tachyphylaxis
5
Q
nitroglycerin + isosorbide [nitrates]
CI
A
sildenafil
glaucoma
HTN
hyperthyroidism
6
Q
nitroglycerin + isosorbide [nitrates]
RN teaching
A
- caution w hot showers, hot days, + dehydration
- avoid ETOH
- monitor BP + HR
- never cut a patch
- remove patch at night
- must be med free 8-12 hr/day to prevent tolerance
7
Q
nitro bid is prescribed in….
A
inches