CV - coronary artery disease

Question 1

what is myocardial ischemia? what happens to the cells?

Answer 1

• a state where the cells are temporarily deprived of blood supply
• the cells remain alive but cant function normally

Question 2

what does persistent ischemia cause?

Answer 2

• causes the acute coronary syndromes

Question 3

what does coronary artery disease diminish? what does this impair? what will this lead to?

Answer 3

• diminishes blood supply
• impairs myocardial metabolism
• leads to myocardial ischemia

Question 4

what is myocardial infarction?

Answer 4

• when prolonged depleted blood supply to the heart causes infarction with myocyte necrosis

Question 5

what are the two types of infarction?

Answer 5

subendocardial or transmural

Question 6

what is the difference between subendocardial and transmural infarction?

Answer 6

• when the thrombus disintegrates before complete tissue necrosis it only affects the endocardium
• if the thrombus is stuck in the blood vessel then there is tissue necrosis that extends through the myocaridum from the endocardium to the epicardium

Question 7

what are the clinical manifestations of myocardial infarction?

Answer 7

sudden severe chest pain, pain that radiates to jaw, arm and neck, nausea and vomiting, indigestion, complications in the GI tract