Cortisol and adrenline Flashcards
what is the resting affects of cortisol
Cortisol causes mobilisation of fuel, skeltal muscle and liver release glucose adipose releases fatty acids.
releases glucagon
Mainstains normal blood pressure
immune suppression (supresses inflamation)
Reduces glucose storeage as glycogen and ketones
What is the release pathway for cortisol
hypothalumus: corticotropin releasing hormone
Anterior pituitary: adrenocorticotropin hormone
Cortex of the adrenal gland: Cortisol secretion
Negative feedback to AP and HT to stop release of CRH and ACTH
What are the three phases of a stress reponse
Alarm phase
resistance phase
exhastion phase
What are the effects of the alarm phase
quickly enduced stress
releases catecholamides = adrenline and noradrenline
Hypothalumus activates the sympathetic nervous system
reponses: increase, mental awareness heart rate breathing, mobilisation of energy,
What is the effect of adrenline and how is it released
Released during a stress reponse from the medulla of the adrenal gland
causes, mobilisation of energy, dilated arways, vacoconstrictions, stronger heart contractions
What is the resistance phase
Resisting the symptoms of stress
Low gycogen reserves due to stress reponse
releases: cortisol + glucagon, adrenline, alderserone, anti diuretic hormone,
Effects:
Fuel mobilisation
Cortisol+glucagon+Adrenline+ growth hormone
increased blood pressure
Aldersterone (increase Na,) Antiduretic hormone(water reabsorbtion + vacoconstrcitions), cortisol
Increased immunity:
cortisol reduces inflamation increasing immunity
What is unique about the fuel mobilisation during stress resistance
Most of the glycogen stores have been burnt through so lots of lipid fats and proteins are broken down to produce energy
Glucose is required by neural tissue so the focus of remainig glucose is on these.
Describe the exhastion phase of stress reponses
Can last weeks -> years
The bodys response to stress is deemed inadiqute and fuel reserves are used up
Linked to: heart conditions, stroke, chronic high blood pressure