corticosteroids

Question 1

Corticosteroids work by

Answer 1

inhibiting the release of inflammatory mediators

Question 2

When applied to inflamed skin, steroids inhibit the ____ of macrophages and leukocytes

Answer 2

migration

Question 3

Factors that increase absorption: h____

Answer 3

hydration

Question 4

Factors that increase absorption: o___ d___

Answer 4

Occlusive dressings

Question 5

Factors that increase absorption: i___ and c____

Answer 5

Infants and children; increased absorption due to increased body surface area

Question 6

formulas: ___ are more occlusive, therefore more potent

Answer 6

Ointments (o for occlusive)

Question 7

Gels, aerosols, lotions and solutions are useful in

Answer 7

hair-bearing areas

Question 8

how long should you use Very high potency

Answer 8

less than 3 weeks

Question 9

steroids are Contraindicated: As ___ in primary bacterial infections, rosacea, or acne vulgaris

Answer 9

monotherapy

Question 10

steroids are Contraindicated: Use of high or very-high potency agents on

Answer 10

face, groin, or axilla

Question 11

Corticosteroids: Prolonged ophthalmic use may cause steroid-induced

Answer 11

glaucoma and cataracts

Question 12

Corticosteroids: Pregnancy Category

Answer 12

C

Question 13

Corticosteroids: Use in children can result in H___, c___, i___

Answer 13

hypothalamic-pituitary-adrenal (HPA) asix suppression, Cushing’s syndrome, and intracranial hypertension

Question 14

Corticosteroids: Chronic high-dose corticosteroid therapy in children may suppress

Answer 14

growth

Question 15

Corticosteroids: Adverse Drug Reactions: __pigmentation

Answer 15

Hypopigmentation

Question 16

Corticosteroid Tolerance; may be reversed by

Answer 16

cycling application

Question 17

Corticosteroids: Systemic effects; ___ failure increases risk

Answer 17

liver

Question 18

Topical corticosteroids have a repository effect-

Answer 18

with continuous use, prolonged action with less frequent applications

Question 19

discontinuing long term high-potency corticosteroids

Answer 19

Do not abruptly discontinue after long term high-potency use-> rebound effect may occur; tapering can prevent this

Question 20

Treatment with very -high potency should not exceed 2 consecutive weeks due to risk of

Answer 20

HPA axis suppression

Question 21

Proper occlusive dressing application

Answer 21

Wash area then soak in water; apply medication to moist skin and gently rub; cover with plastic wrap. Limit to 12-24 hours

Question 22

Prescribe Lower-potency for

Answer 22

application to large areas of the body, and for areas that may be more sensitive, such as the face, eyelids, and groin area.

Question 23

Prescribe Medium-potency for

Answer 23

more severe cases of dermatitis, as well as eczema and scabies

Question 24

Prescribe High-potency for

Answer 24

thick-skinned areas or lesions due to their enhanced penetration