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Pharm > Abx with limirick > Flashcards

Abx with limirick Flashcards

1
Q

Tetracylcines considerations

A

Decreased effect with cal, iron, aluminum. It crosses the placenta

the Tet doesn’t give cal, iron, or aluminum, but they do cross the placenta

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2
Q

Carbapenem ADRs

A

Type 1, type 3
C Dif
Immipenem causes szr

ONE type of Carb causes THREE types of C Dif. Gimme the pen or I’ll seize it

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3
Q

erTAPenem

A

Tap out against Sue, you only live once but it’s a long life

Doesn’t work for pseudomonas, only take once a day because of long half life

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4
Q

Anti-pseudomonal penicillins

A

Piperacillin tazobactam, used for MSSA Anaerobes neg
Piper only comes as IV and given with beta lactam

Piping hot tazo tea, Ms Aneg? I can put it in your IV bag with a nice beta-lact

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5
Q

Nafcillin

A

anti-staph penicillin, needs frequent dosing, the IV form is highly protein bound so there’s less free drug

In the AFC, the Staff makes you dose frequently, and get your protein in an IV

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6
Q

Which abx don’t need renal adjustment

A

doxyclcyine, Naf, ceftriaxone, azithromycin

Diabetics needs to Xamine their Zipper

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7
Q

Gram positive-

A

strep, staph, enterococcus, c dif.

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8
Q

Carbapenems

A

Pos anaerobes neg

carba-PAN-ems

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9
Q

Meropenem

A

1st choice for ESBL and AMPc (tied with dori and imi)

Mera can’t spell so she uses acronyms

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10
Q

Tetracycline uses

A

CAP, alternate to penicillin, MRSA, Ticks, Acne, Syphilis

TetracycLINE: Line up and put on your CAPS, instead of going to the goat PEN, Mr. SA will check your ankle for ticks, your face for acne, and your groin for syphilis

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11
Q

Fluoroquinolones ADRs

A

C diff, QTc, photosensitive

Flora was different from the Q-barn elephants because she liked taking pictures

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12
Q

Doripenem

A

tie for first choice for ESBL and AmpC.

Don’t use dori for pneumonia

Dori forgets everything but don’t bother with a pneumonic device

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13
Q

Moxifloxacin

A

moxifloxacin is the respiratory FQ

Eric Garner said I need mo air

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14
Q

Levofloxacin

A

levofloxacin for pneumonia and UTI

I levitated but a pneu i got a UTI

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15
Q

Azithromycin

A

Doesn’t inhibit P450
Take on empty stomach
excreted unchanged
Post abx effect

Aztecs didn’t live past the year 450, the EMPTIED people’s stomachs, and that NEVER CHANGED. They cleaned the blood with TISSUE, and their legends GO ON even though they’re gone.

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16
Q

Ciprofloxacin

A

Cipro - the best a pseudomonal and providers gram neg double coverage (but not pneumonia which is gram positive)

See, they’re PROFESSIONALS when it comes to PSEUDO wrestling, that’s why they eat DOUBLE cheeseburgers

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17
Q

Clindamycin

A

Use for MRSA, Good tissue penetration, alternate for pen allergy, reduces toxins, good for skin eating infections

c Linda is crying because she got MRSA, give her a TISSUE. She doesn’t use a PEN because it TOXIC to her SKIN

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18
Q

Fidaxomicin

A

Novel macrolide, take it PO, good for c dif.

Ida wrote a novel about people who ATE so much that they got DIARRHEA

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19
Q

Erythromycin

A

erythromycin inhibits the P450, it empties the stomach (promotility)

Early in the morning, in my habitat it’s 4:50am, I get up and empty my stomach

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20
Q

Macrolides in general are for

A

Atypicals, Pneumonia, COPD flare up, urogenital, pylori

Mac was atypical because he had bigs lungs that could flare up, he could run to europe faster than a pylot

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21
Q

Macrolide ADRs

A

GI, eosinophilia, heptatis in pregnancy

Mac from always sunny worked out until he looked like GI Joe, he still lives in Philia with his pregnant wife

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22
Q

Clarithromycin

A

inhibits P450

Clara stops herself from going out past 4:50pm

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23
Q

Bacteriostatic

A

Macrolides, Tetracycline, Sulfonamides, TMP

My TB Skin Test

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24
Q

Penicillin ADRs

A

From rash to anaphylaxis
Onset is up to 30 minutes
Megacolon
Szr

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25
Q

Anti-staph penicillins are good because they are ____ resistant

A

penicillinase resistant

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26
Q

Anti-staph penicillin examples

A

nafcillin, oxacillin, cloxacillin, dicloxacillin

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27
Q

Amoxicillin indication

A

Mostly for upper resp infection

Amox is Almost always at the TOP of the list for resp infection

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28
Q

Ampicillin IV

A

1st choice for listeria and enterococcus

It’s Victor’s 1st choice on my list of entamins

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29
Q

Bactericidal

A

Pigs can fly, geese can molt

Penicillin, cephalosporin, FQs,
Glycopeptides, carbapenems, monobactams

30
Q

Monobactams

A

Only works for negative, cross allergy with ceftazidime

The monorail ended up being negative for springfield, it didnt make a DIME

31
Q

Piperacillin-tazobactam

A

used for MSSA Anaerobes neg
Piper only comes as IV and given with beta lactam

Piping hot tazo tea, Ms Aneg? I can put it in your IV bag with a nice beta-lact

32
Q

How should you use Piperacillin-tazobactam

A

use for extended time period

33
Q

3rd generation cephalosporins

A

the 3 stands for crossing the 3 Bs (BBB)

But…but…but…don’t give with calcium

34
Q

Ceftazidime and cefolozone

A

Dime me out and fly me to the ozone layer. On the plane my ABDOMEN might hurt because I need to URINATE. AMP up the BETA tract to volume ESBL

35
Q

1st gen cephalosporin

A

Think 1 for number 1, as in high concentration in the urine.
Also, if 1 penicillin doesn’t work, use 1st gen ceph

36
Q

Aminoglycoside toxicity

A

Ami-NO-glycoside

Oh no no! (otoxicity, nephrotoxicity, not for pregnancy)

37
Q

First line for strep

A

penicillin G

38
Q

Methicillin is not used much anymore because (besides the obvious reason)

A

renal tox

39
Q

Silver sulfonamide

A

its for the eye (remember because babies get silver)
but it’s also for skin
TMP

40
Q

TMP-SMX interactions

A

they have 3 letters, so 3 interactions, with 3 major things

Increase warfarin, dig, K

41
Q

Aminoglycosides excretion

A

drug clearance is proportionate with creat clearance

42
Q

What’s special about aminoglycoside formulas?

A

it comes in an inhaler

43
Q

Aztreonam is in what class

A

monobactam

44
Q

imipenem is a tie for first with

A

two others for ESBL and AMPc

45
Q

Aminogylcoside examples

A

amikacin, gentamicin, tobramycin

46
Q

Aminogylcoside considerations

A

Post abx effect, No crossing the BBB, work well with cell wall inhibitors, inhibits translocation, one big dose is better then many except for with endorcarditis

SIDE with your political party:
He’s the POSTER boy for No crossing The Wall, Trans-pacific partnership was one big let down.

47
Q

TMP works by attacking bacteria’s

A

folic acid

48
Q

Dicloxacillin

A

dic-LOX-acillin

I just had lox for lunch so I can’t take my dicloxacillin yet

49
Q

TMP uses

A

MRSA, UC, Rheumatoid arthritis, PJP, Prostate/vagina

It’s what Randy took for MRSA.
The UNIT secretary will show you to your RHEUM. Change into hospital PJs before they check your PROSTATE.

50
Q

Sulfanomide ADRs

A

x-allergy with hypoglycemics and thiazides. Not for late pregnancy

Sully flew past the HIPPOS in the bronx zoo, he braced his THIGH before the crash, good thing his PREGNANT wife was too LATE to board the flight

51
Q

Bactram precautions

A

hyponatremia, hyperkalemia

sodium backed out, so the potassium comes out to take its place

52
Q

FQs are not for which 2 kinds of peoples

A

pregnant and kids

53
Q

Ceftriaxone ADRs: s___ and l___

A

sludge and lithiasis

54
Q

Aminoglycoside uses

A

Amina made Tara explode

MDR TB, Endocarditis

55
Q

Two uses for Penicillin G

A

strep and syphilis

56
Q

Gentamicin ADRs

A

remember its an aminoglycoside so the ADRs are ototoxicity and nephrotoxicity

57
Q

Aminoglycosides monitoring

A

Once daily is good, get a level within hours and match to renal function

58
Q

Oxacillin considerations

A

doesn’t cause renal problems but you have to take frequent doses so it’s a pain

59
Q

4th generation Cephalosporin

A

its 4 a lot of things but not anaerobes

broad spectrum but not anaerobes

60
Q

3 FQs that are good for respiratory

A

moxi, levo, gemi

61
Q

5th generation cephalosporin

A

(ceftaroline) Its the newest generation so it works for the toughest thing: MRSA

62
Q

TMP ADRs

A

can be reversed by folic acid

Don’t give with G6PD

63
Q

The 3 older FQs are

A

It’s all a CON

Ciprofloxacin, Ofloxacin, Norfloxacin

64
Q

Ampicillin

A

Take on an empty stomach
Works well with Sulbactam
Needs high doses

65
Q

Cifederocol

A

especially good for carbapenem resistance

think ROCO-Resistance

66
Q

Cephalosporin ADRs

A

cephalopods HAVE ARMS LINED with SUCKERS, THREE hearts, HaveBrains, and are DIFferent than anything else

Hemolytic anemia, Lithiasis, sludge, type 3, HypoprothromBinemia, c dif

67
Q

2 gen Cephalosporins

A

Oral is for pharyngitis, sinusitis, and resp
IV is for abd and periop procedure

2 = Tupac orally rapped until he was hoarse, he got pharyngitis, sinusitis, a resp infection.

Biggie ate too much, got abd infection and had an IV for his periop procedure

68
Q

Tetracyclines: because of the teeth thing, don’t give it to

A

pregnant and kids

69
Q

Measure the ____ if you’re going to use aminoglycosides for a long time.

A

troughs

70
Q

TMP has cross allergy with

A

sulfonamides, oral hypoglycemics and thiazides

Pharm (23 decks)

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