Connective Tissues and Skin (Q2) Flashcards
cells separated by a matrix of loosely or densely packed intercellular material
connective tissue
what does the matrix of connective tissue consist of?
fibers and loose/ dense ground substance
most abundant fixed cell
fibroblast
large star-shaped fixed cell that produces fibers
fibroblast
irregularly-shaped fixed cells used to engulf invaders and damaged cells
fixed macrophages
fixed fat cells
adipocytes
stem cells that respond to local injury or infection by dividing to produce new cells
mesenchymal cells
produce melanin
melanocytes
macrophages that can circulate throughout connective tissue
free macrophages
free macrophages within the blood
monocytes
small, mobile cells near blood vessels that secrete histamine and heparin to stimulate local inflammation in response to injury
mast cells
migrate throughout the body and increase in number where tissue damage occurs
lymphocytes
can develop into plasma cells and produce antibodies
lymphocytes
migrate throughout the body and respond to chemicals released by macrophages and mast cells. these cells are also phagocytic
microphages
examples of microphages
neutrophils and esinophils
thick fibers that occur in long parallel bundles. can withstand much force when pulled along an axis
collagen fibers
fibers that don’t stain well and are difficult to distinguish in microscpy
collagen fibers
thin fibers that form complex networks and are branched. return to original length after stretching
elastic fibers
highly branched with delicate supporting networks
reticular fibers
fibers able to withstand forces applied from many directions
reticular fibers
what composes the extracellular matrix of connective tissues?
ground substance and fibers
what is the function of areolar connective tissue?
strength, elasticity, and support
what is the function of reticular connective tissue?
forms stroma of organs, binds together smooth muscle, filters/ removes worn-out blood cells in spleen and microbes in lymph nodes
what is the function of adipose connective tissue?
reduces heat loss through the skin, serves as an energy reserve, and supports/ connects organs
what is the function of dense regular connective tissue?
strong attachment between bodily structures that withstand the pulling force along the axis of fibers
what is the function of dense irregular connective tissue?
provides pulling strength in multiple directions
what is the function of elastic connective tissue?
allows the stretching of various organs. strong and can recoil to original shape. important to normal lung and elastic artery function
what is the general function of cartilage?
supporting connective tissues
what is the function of hyaline cartilage?
provides a smooth surface for movement of joints; flex and support
what is the function of fibrocartilage?
provides support and joins structures together with a combination of strength and rigidity
what is the function of elastic cartilage?
provides strength and elasticity and maintains the shape of certain substances
where is areolar connective tissue found?
below epithelium in most parts of the body
where is reticular connective tissue found?
bone marrow, spleen, liver, and lymph nodes
where is adipose connective tissue found?
widely distributed throughout the body
where is dense regular connective tissue found?
tendons, ligaments, aponeuroses, and covering skeletal muscle (deep fasciae)
where is dense irregular connective tissue found?
fibrous capsules of organs and joints, periostea, perichondria, nerve and muscle sheaths; makes up the dermis
where is elastic connective tissue found?
walls of the aorta and other blood vessels, in the vocal cords, surrounding respiratory passages, and ligamenta flava and ligamentum nuchae of spinal column. ofter underlies transitional epithelium.
cartilage cells
chondrocytes
where is hyaline cartilage found?
tracheal rings, costal cartilages of the ribs, cartilage of the nose, larynx and covers bone surfaces at synovial joints
what type of cartilage is tough but flexible?
hyaline cartilage
where is fibrocartilage found?
intervertebral discs, makes up the menisci of the knee joint and in the symphysis pubis
what type of cartilage is flexible and durable?
fibrocartilage
where is elastic cartilage found?
pinna, epiglottis, and auditory canal?
one-third of its matrix consists of collagenous fibers?
bone
fluid connective tissues
blood and lymph
what type of connective tissue has a random arrangement of collagen, elastic, and reticular fibers?
areolar connective tissue
what type of tissue contains only reticular fibers?
reticular tissue
what type of tissue has modified fibroblasts which store fat and become swollen?
adipose tissue
what type of tissue has collagenous fibers in regular, parallel arrangement?
dense regular connective tissue
what type of tissue has irregularly arranged collagenous fibers?
dense irregular connective tissue
what type of tissue has largely elastic fibers with fibroblasts imbedded in between?
elastic connective tissue
unfilled spaces in connective tissue
lacunae
what type of cartilage has tightly packed collagen fibers?
hyaline cartilage
what is the weakest type of cartilage?
hyaline cartilage
what type of cartilage has densely-packed, regularly-arranged fibers?
fibrocartilage
what type of cartilage has irregularly-arranged elastic fibers
elastic cartilage
what type of cartilage has lacuna and chondrocytes in regions?
elastic cartilage
what type of connective tissue is avascular?
cartilage
what type of cartilage has paired chondrocytes?
hyaline cartilage
what type of cartilage is the most durable?
fibrocartilage
areloar connective tissue
areolar connective tissue
areolar connective tissue
areolar connective tissue
adipose connective tissue
adipose connective tissue
adipose connective tissue
adipose connective tissue
reticular connective tissue
reticular connective tissue
reticular connective tissue
reticular connective tissue
reticular connective tissue
dense regular connective tissue
dense regular connective tissue
dense regular connective tissue
dense regular connective tissue
dense regular connective tissue
dense regular connective tissue
dense irregular connective tissue
dense irregular connective tissue
dense irregular connective tissue
dense irregular connective tissue
dense irregular connective tissue
elastic connective tissue
elastic connective tissue
elastic connective tissue
elastic connective tissue
hyaline cartilage
hyaline cartilage
hyaline cartilage
hyaline cartilage
hyaline cartilage
fibrocartilage
fibraocartilage
fibrocartilage
fibrocartilage
fibrocartilage
elastic cartilage
elastic cartilage
elastic cartilage
elastic cartilage
elastic cartilage
bone
bone
blood
lymph
what is the most deep layer of skin?
stratum basale or stratum germinativum
what is the second most deep layer of skin?
stratum spinosum
what is the third most deep layer of skin?
stratum granulosum
what layer of skin is found only in thick skin?
stratum lucidum
what is the most superficial layer of skin?
stratum corneum
yellow/orange precursor to vitamin stored in the stratum corneum
carotene
where is carotene stored?
stratum corneum
yellow-red/brown/black pigment formed by melanocytes in stratum basale
melanin
where is melanin formed?
stratum basale
what is the function of melanin?
protecting the nucleus of cells within the epidermis from uv radiation
what are the two regions of the dermis?
papillary and reticular
what is the breakdown of papillary and reticular regions of the dermis?
1/5 papillary and 4/5 reticular
what type of tissue makes up the papillary region of the dermis?
areolar connective tissue
what type of tissue makes up the reticular region of the dermis?
dense irregular connective tissue
attaches to hair follicles and secretes sebum
sebaceous gland
what is the function of sebum?
keep skin soft and moist
produces the stinky smell
apocrine sudoriferous glands
helps with thermal regulation and has no odor
eccrine sudoriferous glands
what is the larger sudoriferous gland
apocrine glands are larger than eccrine glands
soft, short, thin, lightly pigmented hair
vellus hair
longer coarser hair
terminal hair
help pull up the hair when there are goose bumps etc.
arrector pili muscle
what type of muscle is the arrector pili muscle?
smooth muscle
what tactile receptor senses deep pressure/touch
pacinian corpuscle
what tactile receptor senses torsion, twisting, and stretching
ruffini corpuscle
what type of tactile receptor senses fine and light touch in the dermis
meissner corpuscle
what type of tactile receptor senses epidermal fine and light touch
merkel cells
what is the only epidermal tactile receptor?
merkel cells
extend surface area of dermis into epidermis
dermal papillae
a
meissner’s corpuscle
b
ruffini corpuscle
c
pacinian corpuscle
another name for ruffini corpuscle
type ii cutaneous mechanoreceptors
a
eccine sudoiferous gland
b
apecrine sudoriferous gland
a
stratum corneum
b
stratum lucidum
c
stratum granulosum
d
stratum spinosum
e
stratum basale
a
sebacous gland
b
hair follicle
c
arrector pili muscle
a
arrector pili muscle
b
hair follicle
c
sebaceous gland
a
meissner’s corpuscle
b
eccrine sudiferous gland
c
fibroblast
a
stratum corneum
b
stratum granulosum
c
stratum spinosum
d
stratum basale
a
apocrine sudoiferous gland
b
meisner’s corpuscle
c
eccrine sudoiferous gland
d
pacinian corpuscle
a
sebaceous gland
b
arrector pili muscle
c
hair follicle
a
stratum basale
b
stratum spinosum
c
stratum granulosum
d
stratum lucidum
e
stratum corneum
embryonic tissue from which connective tissue originates
mesenchyme
bone-forming cell
osteoblast
cartilage-forming cell
chondroblast
what makes up the ground substance of connective tissue?
large sugar and sugar-protein molecules
only ground substance not produced by the connective tissue it surrounds
plasma
fibrous membrane that wraps around muscle, vessles, and nerves
fascia
ground substance of bones
calcium salts
skin covering the body’s surface (membrane)
cutaneous membrane
lines hollow internal organs
mucous membrane/ mucosa
what is the areolar tissue called as part of the mucous membrane?
lamina propia
lines closed pleural, pericardial, and peritoneal cavities
serous membrane/ serosae
what is the simple squamous epithelia in serosae called?
mesothelium
relatively undifferentiated cells that renew continually to produce new cells as needed
stem cells
strongest skin region
stratum granulosum
what skin layer plans a significant role in slowing water loss across the epidermis?
stratum granulosum
what are the functions of subcutaneous tissue?
insulation and anchoring skin to muscles
3 layers of hair
medulla, cortex, cuticle
where are apocrine sweat glands mostly found?
axial, anal, and genital regions
sebum blocks sebaceous glands causing a greater likelihood of bacteria
acne
rough scaly spots form treated with creams or surgical removal
actinic keratosis
only epidermis is harmed. redness, swelling, and pain
1st degree burns
damage to the epidermis and dermis but not complete destruction. pain and blistering
2nd degree burns
complete destruction of the epidermis and dermis. burning of sweat glands, nerves, and blood vessels. hair loss, more prone to infection, bad for heat loss- oil retention
3rd degree burns
caused by repeated friction, short-term
callus
long-term friction leads to a fluid-filled pouch separating the epidermis and dermis
blister
herpes simplex virus creates marks around lips/mouth
cold sores
poorly-oxygenated hemoglobin causes the skin to turn blue
cyanosis
occur over bone prominence for wheel-chair bound people. epidermis and dermis lost and collagen increases
decubitis ulcers/ pressure ulcers
scaling/ inflammation of various types
dermatitis
staph infection common around school-aged children with pink, fluid-filled spots around the mouth and nose
impetigo
autoimmune disease causing red, scaly inflammation
psoriasis
dilated small blood vessels rupture to cause the face to turn red
rosacea
vitamin D deficiency which weakens collagen and connective tissue. teeth loss, blood vessel rupture, and poor healing
scurvy
general term for skin cancer
carcinoma
most common/ least malignant type of skin cancer
basal cell
basal cells invade the dermis/ subcutaneous tissue
basal cell (skin cancer)
scaly, rounded spots that need to be treated with radiation, surgery, or drugs
squamous cell carcinoma
most deadly type of skin cancer
malignant melanoma
transdermal patch delivery
drug molecules diffuse through the epidermis to dermal blood vessels
loss of melanocytes; autoimmune disease
vitiligo
skin layer made primarily of stem cells
stratum basale
carotene is produced in this layer
stratum granulosum