Connective Tissue Flashcards
Connective tissue
• few scattered cells surrounded by large amounts of extracellular matrix
• Develop from mesoderm
• Cells do not have free surfaces
• Highly vascularized (rich blood supply) + has a nerve supply
2 basic elements
Cells
Extracellular matrix
Fibroblasts
large, flat cells w/ branching processes. In all connective tissues; most abundant. Makes extracellular matrix
Macrophages
phagocytes; monocytes (WBC) —> turns into macrophage in tissue. Gather at sites of infection/inflammation to carry on phagocytosis
Plasma cells
develop from B-lymphocytes; mostly in GI +respiratory tracts
Mast cells
inflammatory reaction to injury+infection , binds to/ kills bacteria
Adipocytes
fat /adipose cells; store triglycerides. Around heart + kidneys
Eosinophils
WBC’s ; migrate to parasitic infection + allergic reaction
Neutrophils
WBC’s ; migrate to infection ,destroy microbes in phagocytosis
Leukocytes (WBC’s)
From blood —> tissue —> sites of parasitic invasions + allergic responses.
Ground substance
connective tissue between cells + fibres;
- Composed of: water + hyaluronic acid + chondroitin sulfate + glucosamine
Extracellular matrix
— in spaces between connective tissue cells
— composed of; fibres + ground substance
Fibres
provide strength + support to tissue
Collagen fibres
collagen ; most abundant protein in our body ; largest
Elastic fibres
elastin + fibrillin ; smaller
Reticular fibres
collagen + glycoprotein ; smallest
Embryonic Connective Tissue
- Mesenchyme
- Mucous
Mature Connective Tissue
- Strong in 1 plane not twist or turn
- Loose ( areolar, adipose, reticular )
- Dense ( regular, irregular, elastic )
Supporting connective tissue
- Cartilage ( hyaline, fibrocartilage, elastic )
- Bone ( compact, spongy )
Liquid connective tissue
- Blood
- Lymph
EMBRYONIC MESENCHYME function
• Forms connective tissue
EMBRYONIC MESENCHYME location
• under skin
• bones of embryo
• blood vessels
EMBRYONIC MUCOUS (mucoid) function
• Support
EMBRYONIC MUCOUS (mucoid) location
• Umbilical cord of fetus
LOOSE AREOLAR function
• Strength • elasticity • support
LOOSE AREOLAR location
• subcutaneous layer;
• blood vessels
• nerves
• organs
LOOSE ADIPOSE function
• Reduces heat loss
• energy reserve
• supports organs
LOOSE ADIPOSE location
• areolar tissue
• subcutaneous layer
• heart
• kidneys
• Yellow bone marrow
• Joints
• eyeball
LOOSE RETICULAR function
• Stroma of organs
• binds smooth mm
• Filters blood cells
• Filters microbes
LOOSE RETICULAR location
• Stroma of liver
• spleen
• lymph nodes
• Red bone marrow
• reticular lamina
• blood vessels
• muscles
DENSE REGULAR function
• strong attachment
between structures.
• Tissue withstands pulling along fibers axis
DENSE REGULAR location
• tendons
• ligaments
• aponeuroses
DENSE IRREGULAR function
• Provides tensile (pulling) strength in many directions
DENSE IRREGULAR location
• fasciae
• dermis
• pericardium, periosteum, perichondrium
• Joint/membrane
• kidneys/liver/testes/ lymph nodes/heart
DENSE ELASTIC function
• Stretches organs • recoil
DENSE ELASTIC location
• Lung tissue
• arteries
• trachea/bronchial
tubes/vocal cords
• penis/vertebrae ligaments
CARTILAGE HYALINE
Weakest cartilage
CARTILAGE HYALINE function
• joint movement
• flexibility
• support
CARTILAGE HYALINE location
• Long bones
• ribs/nose/larynx/
trachea/bronchi/
bronchial tubes
• embryonic bone
CARTILAGE FIBROCARTILAGE
Strongest cartilage
CARTILAGE FIBROCARTILAGE function
• Support + Strength
+ Rigidity
• joins structures together
CARTILAGE FIBROCARTILAGE location
• Pubic symphysis
• intervertebral discs
• menisci of knee,
• tendons in cartilage
CARTILAGE ELASTIC function
• Strength + Elasticity
• maintains shape of structures
CARTILAGE ELASTIC location
• epiglottis
• auricle/eustachian tubes (ear)
BONE COMPACT function
• Support + protection+
storage;
• houses blood-forming tissue
• act with muscle for movement
BONE COMPACT location
• bones
BONE SPONGY function
• Support + protection+
storage;
• houses blood-forming tissue
• act with muscle for movement
BONE SPONGY location
• bones
LIQUID BLOOD function
• RBCs: transport O2 + CO2
LIQUID BLOOD location
• blood vessels
• heart chambers
LIQUID LYMPH function
• RBCs: transport O2 + CO2
LIQUID LYMPH location
• blood vessels
• heart chambers