CNS 29-end Flashcards
name some adverse effects of buproprion
sympathetic stimuation
sleep disruption
dry mouth
what is an adverse effect of rTMS
headache
name some adverse effects of clozapine
agranulocytosis
inc metabolic risks
drowsiness
name some adverse effects of quetiapine
potentially more drowsiness
what is parkinsonism
tremor at rest
rigidity
akinesia
how does ECT work
small electrical currents are applied to the head to stimulate the brain
what is akathesia
feeling of inner restlessness and inability to stay still
what do typical antipsychotics improve
positive symptoms (not negative)
Describe the 3 main effects of serotonin syndrome
autonomic dysfunction
neuromuscular abnormalities
encephalopathy
what is useful to reduce cravings in people trying to quit smoking
Buproprion
name some atypical antipsychotics
clozapine
olanzapine
quetiapine
risperidone
aripiprazole
at what age does schizophrenia occur
20-30 years old
name two non-drug methods of treating depression
repetitive transcranial magnetic stimulation
electroconvulsive therapy
what is malignant neuroleptic syndrome
hyperthermia
muscular rigidity
coma
what is dystonia
sustained inappropriate muscular contractions
grimacing
chlorpromazine
haloperidol are examples of what type of drugs
typical antipsychotics
name more common adverse effects of typical antipsychotics
anti-M
anti H1
anti a1
inc secretion of prolactin
photosensitivity
what atypical antipsychotic is a partial agonist at DA receptors
aripiprazole
what is tardive dyskinesia
involuntary repetitive movements
name some negative symptoms of psychosis
passivity
alogia
anhedonia
lack of concentration
social isolation
lack of initiative
tremor at rest
rigidity
akinesia
Parkinsonism
name some adverse effects of olanzapine
inc metabolic risks
drowsiness
name 2 typical antipsychotics
chlorpromazine
haloperidol
sustained inappropriate muscular contractions
grimacing
dystonia
name 3 5HT+NA reuptake inhibitors
venlafaxine
duloxetine
desvenlafaxine
what is lithium used to treat
bipolar disorder
what are some adverse effects of ECT
headaches
muscle soreness
amnesia
what is another name ofr bipolar
manic depressive illness
feeling of inner restlessness and inability to stay still
akathesia
what are some advantages of SNRIs
faster therapeutic effect (potentially)
what does SHIVERS describe
effects due to serotonin syndrome
name some adverse effects of lithium
nausea
thirst
polyuria
fine tremors
why can aripiprazole be beneficial
fewer adverse effects related to excessive blockade of DA receptors
less sedative effect
less weight gain
fewer metabolic effects
what are the two types of antipsychotics
typical
atypical
do typical antipsychotics improve positive or negative symptoms
positive
name some risks of aripiprazole
inc risk of pathological gambling and hypersexuality
what is the MOA for typical antipsychotics
they block DA receptors in the brain
how does rTMS work
magnetic pulses are used to increase activity in parts of the brain
why can atypical antipsychotics be better than typical
affect serotonin and other NTs instead of just DA
improve both positive and negative symptoms
fewer extrapyramidal effects
what does SHIVERS stand for
shivering
hyperreflexia/clonus
increased temp
vital sign instability
encephalopathy
restlessness
sweating
what drug can be used to treat bipolar
lithium
name a NA+DA reuptake inhibitor
Buproprion
name some positive symptoms of psychosis
hallucinations
strange language
disorganized behaviour
agitation
repetition of movement
inappropriate gesticulaiton
name 3 extrapyramidal symptoms
parkinsonism
dystonia
akathesia
describe schizophrenia
difficulty in sharing an interpretation of reality with others
what is psychosis
mental state characterized by loss of contact with reality
name 3 major adverse effects of typical antipsychotics
extrapyramidal symptoms
tardive dyskinesia
malignant neuroleptic syndrome
why can lithium be dangerous
narrow TI
seizures at high doses
