clinical connections Flashcards
skin grafts
transfer of a patch of healthy skin taken from a donor site to cover wound
autologous skin transplantation
if the skin damage is so great, a self-donation procedure…for severely burned patients a small amount of epidermis is removed and keratinocytes are cultured to create sheets of skin
apigraft and transite skin graftsare grown where and from what
grown in laboratory from the foreskins of circumcised infants
what provides clues for diagnosing certain conditions
colour of skin and mucous membrane
cyanosis
due to lack of oxygen, skin appears bluish
jaundice
buildup of bilirubin in blood, yellowish appearance to the skin and whites of eyes..liver issue
erythema
redness of skin caused by engorgment of capillaries in the dermis with blood due to skin injury, exposure to heat, infection, inflammation, allergic reaction
pallor
paleness of skin…shock or anemia
chemotherapy-what is it, what does it interupt, what loses stuff
treatment of disease, usually cancer, using chemical substances or drugs
-chemotherapeutic agents interrupt the life cycle of rapidly dividing cancer cells
-hair loss, 15% stay in resting state so it stays
acne
inflammation of sebaceous glands that usually beings at puberty, when the sebaceous glands are stimulated by androgens
where does acne occur
in sebaceous follicles that have been colonized by bacteria
transdermal (transcutaneous) drug administration
enables a drug contained within an adhesive skin patch to pass through the epidermis and into the blood vessels of the dermis
transdermal (transcutaneous) drug administration examples and what it does
-nitroglycerin- prevention of angina pectoris…chest pain with heart disease
- scopolamine…motion sickness
- estradiol…estrogen replacement therapy during menopause
- ethinyl estradiol and norelgestromin in contraceptive patches
- nicotine to help stop smoking
- fentanyl- relieve severe pain in cancer patients
bone scan-how is it administered, what indicates abnormlities, why is it important to do, what does it do
intravenous
figures out the amount of blood flow to bone
darker or lighter areas indicated abnormalities
standard test for bone density screening….important for females for checking for osteoporosis
bone scan-darker areas
hot spots
indicate bone cancer, abnormal healing of fractures, abnormal bone growth…areas of increased metabolism…increased blood flow
bone scan- lighter areas
cold spots….decreased metabolism absorbs less radioactive tracer due to decreased blood flow
degenerative bone disease, decalcified bone, fractures, bone infections, paget’s disease, rheumatoid arthritis
orthodontics
dentistry that focuses on the prevention and correction of poorly aligned teeth…osteoclasts and osteoblasts remodel the sockets so teeth align properly
giantism
oversecretion of growth hormone during childhood
dwarfism and 2 types
small stature…under 4 feet 10 inches
2 types: proportionate and disproportionate dwarfism
proportionate dwarfism
all parts are small but proportionate to eachother
hyposecretion of GH and condition called pituitary dwarfism…can be treated until epiphyseal plate closure
disproportionate dwarfism
some parts are normal, others are small
achondroplasia…conversion of hyaline cartilage to bone is abnormal and long bones stop growing in childhood
achondroplastic dwarfism-disproportionate
short stature but normal head and trunk size
temporomandibular joint syndrome
improperly aligned teeth, grinding or clenching teeth, trauma to head and neck or arthritis
-dull pain around ear, tenderness of jaw muscles, clicking/popping noise when opening or closing mouth
celft palate
incomplete fusion of the palatine bones, failure to unite maxillary bones during week 10-12 of embryonic development
surgical fix 12-18 months of age