Clase Hiperprolactinemia Flashcards

1
Q

Valores normales de prolactina

A

Mujeres <25

Hombres <20

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2
Q

Principal causa de hiperprolactinemia patologica

A

Microprolactinoma

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3
Q

Valores de hiperprolactinemia

A

Mujeres > 25

Hombres > 20

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4
Q

Causas farmacológicas de hiperprolactinemia

A

Antagonistas del receptor D2 –> Antipsicoticos: Risperidona, Amisulprida
ISRS: Sertralina
Metoclopramida

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5
Q

Causas tumores de hiperprolactinemia

A

Microadenomas <1 cm en mujeres de 20-50 años (90%)

Macroadenomas > 1cm o >10 mm después de los 50 años, igual en hombres y mujeres

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6
Q

Niveles de prolactina para sospechar de una macroadenomas

A

> 100 ng/ml

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7
Q

Manifestaciones clínicas de hiperprolactinemia

A

Oligomenorrea, cefalea, galactorrea, infertilidad, disminución de libido, alteraciones visuales (hemianopsia bitemporal) en hombres impotencia
Tardia: osteoporosis

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8
Q

Goldstandar

A

Cromotografia de filtración en gel

Alternativo: prueba de polientilenglicol

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9
Q

Estudio de imagen considerado GOLDSTANDAR para el diagnostico de hiperprolactinemia

A

RM + gadolinio

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10
Q

Tratamiento farmacologico

A

Agonistas de dopamina

  1. Cabergolina: tx 1 año
  2. Bromocriptina
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11
Q

Indicaciones de cirugia

A

Tumor hipofisario y datos clínicos de craneohipertensivos

Alteraciones campimetricas

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12
Q

Criterios de referencia a endocrinologia

A

Prolactina >100 ng/ml
Sintomas de hipogonadismo y galactorrea
Px con adenoma hipofisario en estudio de imagen
Hiperprolactinemia y deficiencia de una o mas hormonas hipofisarias
Datos de compresión

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