Circulatory System Flashcards
Responsible for carrying oxygen, nutrients, hormones. Remove waste products like carbon dioxide from the body.
Circulatory System
Circulatory System is composed of the following?
Blood
Vascular System
Heart
Vascular System is composed of?
Capillaries
Veins
Arteries
What is this function of Circulatory System?
Through blood vessels, the blood is transported from the heart to all body tissues for proper body functioning.
Carries Blood.
What is this function of Circulatory System?
Hormones, components of the immune system, molecules (required for coagulation), nutrients, gases, waste products.
Transports substances.
What is this function of Circulatory System?
Through proper functioning of the heart and circulatory system to maintain normal pressure within normal range of values.
Helps regulate blood pressure.
What is this function of Circulatory System?
Maintain body homeostasis (self-regulating process in which living organisms can maintain normal stability while adjusting to changing external environments).
Directs blood flows to tissue.
Another function of the Circulatory System.
Exchange nutrients, waste products, and gases with tissues.
Transporting fluid of the body in this system.
Blood
55% of blood
Plasma
Percentages of this components in the blood:
water
protein
other solutes.
91% water
7% protein
2% other solutes.
Liquid portion of blood without its cellular elements
clear cellular matrix.
Blood contains different proteins what are they?
Albumin (most abundant) Globulin
Fibrinogen (for blood clotting)
Prothrombin.
name given to plasma after a blood clot is formed, does not contain fibrinogen.
Serum
Formed Elements: _____ of blood
45%
1% ___________, 99% RBCs.
buffy coat
red blood cells
Erythrocytes
white blood cells
Leukocytes
platelets
Thrombocytes
- Biconcave shaped.
- No nucleus.
- Cytoplasm densely filled with hemoglobin.
Red Blood Cells
Lifespan of Red Blood Cells.
120 days
Total RBC count: (in microliter)
Female: 4.2–5.4 x 10^12/L
Male: 4.5–6.2 x 10^12/L
formation of blood cells (RBCs, WBCs, platelets).
Hematopoiesis
process by which RBCs are produced.
Erythropoiesis
Body’s natural defense against injury and disease. Have nuclei and no pigment.
White Blood Cells
Types of WBC based on the ________ of their cytoplasmic granules and there of also type of WBC based on their ________.
density
functions
obvious granules, granulated, have polymorphic nuclei with two or more lobes.
Granulocytes
Examples of Granulocytes
neutrophils, eosinophils, basophils
few or no granules, do not have specific granules but have azurophilic granules (lysosomes), nucleus is round or indented.
Agranulocytes
WBCs that use phagocytosis to engulf bacteria, viruses, and other foreign particles to protect the body.
Phagocytes
Example of Phagocytes
basophils, neutrophils, eosinophils, monocytes
usually involved or related in the immune response of the body.
Immunocytes
Total WBC count.
3.6–10.6
- 3 to 5 nuclear lobes (respond to bacterial infections).
- Specific granules stain light pink.
- Responds to bacterial infection.
Neutrophils
Percentage of Neutrophils
50% to 70%
- 2 nuclear lobes, bi-lobed (respond to parasitic infections and allergy).
- Specific granules stain red-orange.
- Responds to parasitic infection and allergy.
Eosinophils
Percentage of Eosinophils
1% to 4%
- 2 nuclear lobes, often difficult to see (respond to hypersensitivity reactions through histamine release).
- Specific granules stain blue-black.
- Responds to hypersensitivity reactions through histamine release.
Basophils
Percentage of Basophils
0% to 2%
- Spherical nucleus that stains dark blue.
- Responsible for long-term immunity.
Lymphocytes
Percentage of Lymphocytes
20% to 40%
This type of Lymphocytes directly attack an infected or cancerous cell, from the thymus gland.
T-Lymphocytes
This type of Lymphocytes produce antibodies against specific antigens, synthesized in the bone marrow.
B-Lymphocytes
- Indented, C-shaped, horse-shoe or kidney-shaped nucleus that stains blue.
- Phagocytizes bacteria, dead cells, cell fragments and other debris within tissues.
Monocytes
Monocytes migrate into tissues where they transform into?
macrophages
Monocytes is the _________ blood in peripheral blood.
largest
- Most abundant of the formed elements.
- Non-nucleated.
- Promotes blood clotting.
Platelets
Fragments of larger bone marrow cells called?
megakaryocytes
Platelet life spans
10 days
Platelet count
150–450 x 10^9/L
Blood vessel walls consist of 3 layers EXCEPT in?
capillaries
- Innermost layer (exposed to the blood).
- Simple squamous epithelium (endothelium) and thin subendothelial layer of loose connective tissue.
Tunica intima or interna
small amount of connective tissues and a simple squamous epithelium.
Endothelium
Tunica intima has _________ which separates the tunica intima from the tunica media.
internal elastic lamina
Internal elastic lamina is composed of _______ with holes that allows the diffusion of substances to nourish cells in the blood vessel.
elastin
- Middle and the thickest layer.
- Smooth muscle and external elastic tissue.
Tunica Media
Smooth muscle and External elastic tissue of Tunica Media allows?
the blood vessel to change in diameter
Tunica Media has an _____________________ which separates the tunica media from the tunica adventitia.
external elastic membrane
- Outer layer.
- Made up of strong, flexible fibrous connective tissue
Tunica Adventitia or Externa
The strong, flexible fibrous connective tissue of Tunica Adventitia.
Type I collagen and elastic fibers
Type I collagen and elastic fibers ________ and _________ the blood vessels.
supports
protects
- Most common and the smallest blood vessels.
- Connect the arterioles with venules.
Capillaries
Metabolic exchange between blood and surrounding tissues via diffusion to transcytosis.
“Exchange vessels.”
The most common type of capillaries.
Continous
This type of capillary has small circular fenestrae through the very thin squamous epithelial cells.
Fenestrated
Where can Fenestrated be found?
kidneys
intestines
endocrine glands
This type of capillary permits maximal exchange of macromolecules between tissues and blood.
Sinusoidal
Carry oxygenated blood to all parts of the body.
Arteries
conducting arteries
Elastic Arteries
Elastic Arteries has the largest diameter and?
thickest wall
Elastic Arteries expand as blood surges into them and recoil when?
ventricles relax
Examples of Elastic Arteries.
aorta and common carotid artery
distributing arteries
Muscular Arteries
Muscular Arteries is medium-sized and has a?
small diameter
Muscular Arteries Carry blood further away from the heart to?
specific areas of the body
Examples of Muscular Arteries.
brachial
femoral
renal arteries.
This artery delivers blood to capillaries and is the smallest artery.
Arterioles
Principal Artery of Head and face.
Common Carotid
Principal Artery of Brain, orbits (eye) and 80% of cerebrum.
Internal Carotid
Principal Artery of Face, supply most of the external head structures.
External Carotid
Principal Artery of Spinal column and brain.
Vertebral
Principal Artery of Right arm, head and shoulder.
Brachiocephalic
Principal Artery of Shoulder.
Subclavian
Principal Artery of Axilla, continuation of the subclavian artery.
Axillary
Principal Artery of Upper arm and elbow area, continuation of axillary artery, artery of the most often used for routine blood pressure measurement.
Brachial