Cell Anatomy Flashcards
A cell is defined as the __________ that is responsible for all of life’s processes.
smallest, basic unit of life
Humans have more cells compared to?
Bacteria
This is the study of cells from its basic structure to the function of every cell organelle.
CELL BIOLOGY
Who discovered the cell in 1665?
Robert Hooke
Consequently, he named those rooms as cells however he cannot see any details to those cells because he is only using what type of microscope?
Compound Microscope
2 types of cell
Prokaryotes and Eukaryotes
Fuctions of cell
Metabolize and release energy
Synthesize molecules
Communication
Reproduction and Inheritance
No Nucleus and a single celled microorganism
Prokaryotic Cell
True Nucleus and a multicellular organism
Eukaryotic Cell
Contains genetic material of the cell (DNA) and nucleoli; site of RNA synthesis and ribosomal subunit assembly.
Nucleus
How is RNA created?
through transcription of DNA
Has many ribosomes attached; site of protein synthesis
Rough Endoplasmic Reticulum (RER)
Site of lipid synthesis; participates in detoxification
Smooth Endoplasmic Reticulum
Smooth Endoplasmic Reticulum stores also what?
Calcium
Site of protein synthesis
Ribosomes
Modifies protein structure and packages proteins in secretory vesicles.
Golgi Apparatus
Contains materials produced in the cell; formed by the Golgi apparatus; secreted by exocytosis.
Secretory Vesicles
Contains enzymes that digest material taken into the cell
Lyzosomes
Site of aerobic respiration and the major site of ATP synthesis (power).
Mitochondrion
Facilitate the movement of chromosomes during cell divisions.
Centrioles
Supports cytoplasm;assists in cell division and forms components of cilia and flagella. Has structures that give stability to cells.
Microtubule
Move substances over surfaces of certain cells. You can see these in our Respiratory and Digestive system.
Flagella
Increase surface area of certain cells for absorption and secretion modified to form sensory receptors. Usually found in Digestive system. (Organs that are responsible for absorption like small intestines.)
Microvilli
Outermost component of cells. Made out of Phospholipid layers which are double layers.
Plasma membrane
Boundary separates the substance inside the cell (________) to the substance outside the cells (_________)
INTRACELLULAR
EXTRACELLULAR
Ability to ___________ and __________ with other cells through plasma membrane
recognize
communicate
It determines what moves into and out of the cells.
Selective Permeable Membrane
PISO
Potassium In and Sodium Out
45-50% - lipids
45-50% -
4-8% -
Composition of Plasma Membrane
proteins
carbohydrates
Plasma Membrane is divided with your ___________ and ____________
Lipids of Plasma Membrane
phospholipid
cholesterol
In plasma membrane the Cholesterol in it gives?
strength and flexibility
This percentage in plasma membrane act as a membrane channel, the one that regulates ions.
Proteins
glycolipids + glycoproteins =
Glycoproteins
Glyco means?
Carbohydrates
This glyco is responsible for stability and cell to cell communication.
Glycolipids
This glyco are for cell recognition or self recognition, they are also responsible for attachment or bind of other cells.
Glycoproteins
Comprises the total weight of cell.
Water
The term for the combination of glycolipid and glycoproteins
Glycocalyx
Another term for Phospholipid Bilayer
Fluid Mosaic Model
Why is the head of our Phospholipid Bilayer on top (labas) and not below (loob)?
The head of phospholipid is hydrophilic (water loving) and since our cell is immersed in interstitial fluid. Which means tails cannot be in there since they are hydrophobic.
Flat among the phospholipid molecules.
Protein Molecules
Proteins that are on the surface of plasma membranes.
Peripheral
Proteins that are deeply integrated in your plasma membrane.
Integral
Cells to identify one another
Marker Molecules
Receptors that can attach or receptor to a specific chemical.
Receptor proteins
Attachment of cell to another cell
Cadherins
it is the attachment of a cell to extracellular material.
Integrins
Cadherins and Integrins are?
Attachment Proteins
Channel, Carrier, ATP power pumps are?
Channel Proteins
Leaked Ion and Gated Ion
Channel
Channel that is when it is leaking or open, especially when the plasma membrane is at rest.
Leaked Ion
This channel opens and closes of the open entrance of specific ion an metals,
Gated Ion
Carries a specific ion or molecules across the plasma membrane.
Carrier
refers to the transport of one molecule across the plasma membrane
Uniport
movement of two different ions or molecules (glucose and insulin) that transports or move across the plasma membrane in the same direction (sabay)
Symport or Cotransport
Refers to the movement of two different molecules transporting across the plasma membrane in different directions.
Antiport or CounterTransport
Antiport’s energy came from?
ATP power pumps
Increases the rate of chemical reaction.
Enzymes (Catalyst)
found higher concentration intracellularly
Potassium Ion (K+)
are found to be concentrated extracellularly.
Soduim (Na), Calcium (Ca), Iron (Cl)
Fluid outside cells. Rich, nutritious “soup” - amino acids, sugars, fatty acids, vitamins, hormones, salts, wastes
Interstitial Fluid
Plasma membrane only allow some substances to enter cell by what?
Passive or Active Transport
NiWo
Nutrients In Waste Out
This membrane transport, cell does not expend metabolic energy (ATP).
Passive Transport
What’s the substance for diffusion?
Solute
What’s the substance for Osmosis?
Water
Solutes, such as ions or molecules, tend to move from an area _______________ of a solute to an area of _________________ of that same solute in solution. (concentration gradient)
Diffusion
higher concentration
lower concentration
Solution is generally composed of one or more substances which we call?
Diffusion
solute
What is the universal solvent?
Diffusion
Water
Diffusion results from the natural, ___________________ of all solutes in a solution
Diffusion
constant random motion
Specific non-lipid-soluble molecules diffuse through membrane channels
Therefore if it is lipid-soluble?
Diffusion
it cannot pass through the plasma membrane.
Solutes are the ones dissolved in?
Diffusion
predominant liquid organ
Lipid-soluble diffuses ___________ while non-lipid-soluble it will need a ___________.
Diffusion
directly
membrane channel.
Other non-lipid-soluble molecules or ions, for which membrane channels are? Cannot enter the cell
Diffusion
not present in the cell
This is the diffusion of H2O
Osmosis
Osmosis
Osmosis is selectively permeable by?
Osmosis
membrane allows water but not all solutes dissolved in water through it.
Water moves from _________ (fewer solutes, more water) ___________ (more solutes, less water)
Osmosis
less concentrated solution
into more concentrated solution
The resistance of water to pass through a concentrated solution.
Osmosis
Osmotic pressure
Osmosis
The greater the tendency to pass through the concentrated solution then the __________ the osmotic pressure.
Osmosis
higher
The greater the tendency for water to ___________ into the solution, and the greater the osmotic pressure to ___________ that movement.
Osmosis
move
prevent
Examples of fat-soluble-vitamins
Osmosis
ADEC
Same concentration of solute and Osmotic pressure
Osmosis
Isosmotic
Higher Concentration of Solute and Higher Osmotic Pressure
Osmosis
Hyperosmotic
Lower Concentration of Solute and Lower Osmotic Pressure
Osmosis
Hyposmotic
The ability of solution to change shape or tone of cells by changing water volume.
Osmosis
Osmosis: Tonicity of Cells
equal concentration solutes
Osmosis
Isotonic
higher conc. of solutes (Example: IV fluid since it consists of electrolytes, sodium potassium, and glucose)
Hypertonic
lower conc. of solutes (Example: NSS or Normal Saline Solution)
Hypotonic
What’s the substance in facilitated transport?
Facilitated Transport
Solute
A mediated transport process by which transport mediates or assists the movement of large, water-soluble molecules or electrically charged molecules.
Facilitated Transport
Facilitated Transport
Rate of ions is __________ to concentration gradients when all carrier proteins are occupied.
Facilitated Transport
directly proportional
Energy (ATP) is needed. Move molecules against concentration gradient from low to high concentration.
Active Transport
Types of Active transport?
Primary and Secondary
Directly uses ATP to drive transport
Primary Active Transport: Antiport
Antiport is also known as counter-transport which refers to the movement of two different ions or molecules in ___________ across the plasma membrane. (sodium potassium and calcium pump)
opposite directions
Also known as cotransport which refers to the movement of two different ions or molecules in the same direction across the plasma membrane.
Secondary Active Transport: Symport
It requires 2 transport proteins:
A _________ pump actively moves NA+ out of the cell.
A _________facilitates the movement of Na+ and glucose into the cell.
Na+-K+
carrier protein
The thicker conservation of your sodium whichusually should be higher concentrated outside the cell.
Sodium-Potassium
Sodium ions would go back into the cell through transport protein which also moves your?
Glucose
Sodium provides what? Which is required for movement of our glucose against the concentration gradient.
Energy
Fluid and large particles are transported across membranes in vesicles (sacs).
Vescular Transport
“out of cell” - eject substances
Exocytosis
“within the cell” - ingest substances
Endocytosis
This type of endocytosis is (cell eating) engulf large or solid material. Example: WBC engulfing a bacteria
Phagocytosis
This type of endocytosis is (cell drinking) fluid with dissolved molecule.
Pinocytosis
This type of endocytosis concentrates specific substances (ligands) that bind to receptor proteins (assistant). The receptor attaches specific molecules so that it can be brought inside the cell. Example: Insulin, Iron, and Cholesterol
receptor-modiated endocytosis
Makes distinct gametes (diploid to haploid)
Meiosis (Sex Cells)
Clones body cells (diploid to diploid)
Mitosis (Somatic Cells)
Interphase has how many inner phase?
3
This phase is in interphase where it is consider the preparation or cell metabolism. Cellular content excluding the chromosomes are being duplicated and all the cellular metabolism are being finished.
G1 phase
How long does G1 phase lasts?
8 to 12 hours
This process of interphase is where the DNA replication proper happens where each of 46 chromosomes is being duplicated. Synthesization of histones and proteins in nucleus.
Synthetic (S) Phase
How long does Synthetic (S) phase process?
6 to 8 hours
This process of interphase is when all duplication processes and cellular metabolism. Cell division respiration.
G2 Phase
How long does G2 phase process?
4 hours
Phase: The centrioles move to the opposite sides. There’s a condensation of chromosomes.
Prophase
Phase: Chromosomes are aligned at the center or near the center (equatorial plate).
Metaphase
Phase: Chromatids split. They are being pulled out in the opposite direction.
Anaphase
Phase: Forms cleavage furrow
Telophase
After: When they start to divide. The cleavage furrow forms and eventually the cytoplasm of parental cell splits when this is completed your interphase begins again.
Cytokinesis
Disorder in cell structure where the cell decrease in size.
Atrophy
Disorder in cell structure where the cell increase in size.
Hypertrophy
Disorder in cell structure where the cell increase in number.
Hyperplasia
Disorder in cell structure with ability to change into another type of cell.
Metaplasia
Disorder in cell structure where there’s changes in cell structure.
Neoplasia
Disorder in cell structure where it decrease in the amount of oxygen in the blood flow to cellular structure. It is also the cause of ischemia.
Hypoxia