circulatory Flashcards
what is the blood comprised of?
55% plasma and 45% cells(rbc, wbc, platelets)
what is the function of blood?
transport oxygen to cells, maintain homeostasis, arrest haemorrhage through clotting and defend against disease
what is the function of rbc
aka. erythrocytes and they function to transport oxygen to cells from the lungs and take up CO2 from cells and transport it back to the lungs
what are characteristics of rbcs
erythrocytes; have no nucleus, few organelles, are disc-shaped and contain hemoglobin. they circulate for 120 days then are broken down in the spleen(hemolysis).
what are immature rbcs called
reticulocytes
what is the ratio of rbcs to blood?
5 million rbc per mL of blood.
what is the function of wbcs?
defend against disease; fight bacterial infection and remove foreign material
what are wbcs called
leukocytes
what is the function of platelets
play a role in clotting blood, play a role in wound healing and maintain homeostasis(by preventing blood loss)
what are platelets called
thrombocytes
what are some characteristics of platelets?
no nucleus, contain granules of clotting factors and other substances. they are not whole cells, but pieces of megakaryocyte cells.
characteristic of wbcs
contain a nucleus.
what is the composition of plasma
water(90%), protein(8%), mineral salts, nutrients, cellular waste products, hormones, enzymes, antibodies, dissolved gases(O,N CO2)
describe process of blood clotting
- damaged endothelium
- temporary plug formed by platelets; which release thromboplastin
- thromboplastin converts prothrombin to thrombin
- thrombin converts fibrinogen to fibrin
- fibrin traps wbcs and rbcs
what is blood clotting called
coagulation
what mineral does prothrombin need to convert to thrombin?
calcium
describe pathway of blood
Deoxygenated blood enters through inferior or superior vc, into right atrium, where it is pumped through tricuspid valve to right ventricle, where it is pumped through pulmonary valve to pulmonary artery, which pumps the deoxygenated blood to the lungs, where it is oxygenated. It comes back through pulmonary veins into left atrium, its pumped through mitral valve, into left ventricle, then through aortic valve, into aorta, where it is pumped to the rest of the body.
describe sequence of events in cardiac cycle
- Atrial systole(atria contact together)
- Ventricular systole(ventricles contract together)
- diastole(all 4 chambers at rest)
*lasts for 0.8 s and resting HR is usually 72 bpm
describe electrical conduction system of heart
Parasympathetic nerves control HR set by SA node(aka. Pace maker)
Resting HR is 72-75 bpm.
Sympathetic nerves innervate SA node, AV node and myocardium(muscular layer)
This increases hr and contractility of ventricles, especially left ventricle.
what is normal systolic bp
80-120 mm Hg