Chronic Disorder of Neurologic Functions Flashcards

1
Q

This type of disorder is transients neurologic event of paroxysomal abnormal electrical charges that are manifested by disturbances of skeletal motor fxn, sensation, autonomic visceral fxn, behavior, pr consciousness?

A

seizures

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2
Q

what triggers a seizure?

A

is often triggered by a specific stimuli which is usually unique for each individual

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3
Q

Seizure pathogenesis

A

an alt in membrane potential that makes certain neurons abnormally hyperactive and hypersensitive to changes in their environment. neurons can also recruit other neurons in the same region

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4
Q

What are the 2 types of seizures?

A

partial and generalized

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5
Q

Partial seizure

A

electrical disturbance occurs in one hemisphere of the brain

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6
Q

Generalized seizure

A

electrical disturbance occurs in both hemispheres of the brain and produces loss of consciousness

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7
Q

What are the subtypes of partial seizures?

A

simple- consciousness is retained

complex consciousness is impaired or lost

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8
Q

What are the types of generalized seizures?

A
  1. absence
  2. atonic
  3. myoclonic
  4. tonic-clonic
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9
Q

absence generalized seizures

A

occur mostly in children. Lapse of awareness sometimes with staring, begin and end abruptly and lasts only a a few secs

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10
Q

Atonic generalized seizure

A

sudden and complete loss of muscle tone (head drops, loss of posture, collapse)

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11
Q

Myoclonic generalized seizures

A

brief contractions of muscles occasionally involves one arm or foot

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12
Q

Tonic-clonic generalized seizures

A

begin with stiff limbs, muscle contractions, jerking of the limbs and face, breathing may decrease or cease, producing cyanosis of lips, nail beds, and face

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13
Q

What type of syndrome is characterized by a progressive deterioration and continuing decline of memory and other cognitive fxns?

A

dementia

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14
Q

what are the main types of dementia?

A

Alzheimer and vascular-type

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15
Q

What is the most specific change in the bran of those with Alzheimer disease?

A

deposition of extracellular amyloid plaques

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16
Q

Damages in the brain of those with Alzheimer have changes in which mechanisms?

A
  1. nerve cell communication
  2. metabolism
  3. repair
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17
Q

If Elieen has Alzheimer, what neurotransmitters can you expect to be imbalanced?

A

Ach, glutamate, dopamine and serotonin

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18
Q

What are the results of vascular dementia?

A

cerebrovascular insults, multiple lacunar infarcts, and microvascular pathology

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19
Q

What are the risk factors for vascular dementia?

A
  1. stroke
  2. hypertension
  3. diabetes
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20
Q

What are the risk factors for Alzheimer?

A
  1. age
  2. fam history
  3. lifestyle
  4. head trauma
  5. diabetes
  6. depression
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21
Q

What is the mobility disorder that affects 1 million Americans?

A

parkinson’s disease

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22
Q

T/F Parkinson’s disease can be idiopathic and acquired?

A

true

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23
Q

What are common causes of Parkinson’s?

A

infection, intoxication, and trauma

24
Q

Pathogenesis of Parkinson’s

A

degeneration of the pigmented dopaminergic neurons found in the substantia nigra. the cause of degeneration is uknown, but 75%-80% of neurons die before any Sx become apparent

25
What are the early Si of Parkinson's?
loss of flexibility, aching and fatigue
26
What is the Si that patients experience causing them to visit the dr?
tremors
27
What is the cure for Parkinson's?
there is no cure just treatment aiming to slow the progression and Sx management
28
If Rachel is currently taking haloperidol what disease is she at risk for developing?
Parkinson's
29
Cerebral palsy
diverse group of crippling syndromes that appears during childhood and involves permanent, nonprogressive damage to the developing brain
30
Where does damage to the brain occur during cerebral palsy?
upper motor neurons that control voluntary and involuntary muscle movement
31
Cerebral palsy etiologic factors
prenatal infections, disease of the mother, mechanical trauma to the head before, during or after birth, exposure to nerve-damaging poisons, period of reduced oygen to the brain
32
SI/SX of cerebral palsy
hemiplegia, paralegia, triplegia, and quadriplegia, slow and jerky movements,
33
Condition caused by abnormal accumulation of CSF in the cerebral ventricular system
hydrocephalus
34
What are the 3 types of hydrocephalus?
1. normal-pressure- CSF vol increases without change in ICP because brain tissue has been lost 2. Obstructive/noncommunicating- most common in children and attributable to an abnormality of the cerebral aqueduct or a lesion in the fourth ventricle 3. nonobstructive/communicating- abnormality in the capacity to absorb fluid from the subarachnoid space
35
What are some cause of cerebellar disorders?
abscess, hemorrhages, tumors, trauma viral infections, and chromic alcoholism
36
Si/Sx of cerebellar disorder
ataxia (muscle incoordination), hypotonia, intention tremors, disturbances of gait and balance
37
MS
A chronic demyelinating disease of the CNS that causes significant disability in young adults
38
MS Etiology
autoimmune disorder that results in inflammation and scarring of the myelin sheaths covering nerves
39
What are the structures most affected by MS?
optic nerves, oculomotor nerve, and the corticospinal, cerebellar, and posterior column systems
40
SI/SX of MS
blurred vision, diplopia, weakness, numbness, tingling, extreme fatigue, imbalance, pain, paraesthesia, cognitive impairment, and vertigo
41
Spina Bifida
developmental anomaly characterized by defective closure of the bony encasement of the spinal cord (neural tube) through the spinal cord and meninges may or may not protrude
42
What is the difference between spina bifida occulta and spina bifida cystica?
Occulta there is no visible anomaly and cystica there is an external saclike structure
43
Supplementation of what should be consumed during pregnancy to reduce the risk of spina bifida?
folic acid
44
ALS
A progressive degenerative disease affecting both the upper and lower motor neurons characterized by muscle wasting and atrophy of the arms, hands, and legs
45
What has been identified as the only probable cause of ALS currently?
smoking
46
SI/SX of ALS
muscle weakness and atrophy (earliest: twitching, cramping, and stiffness)
47
What is the common treatment for ALS?
Glutamate inhibitor
48
What are spinal cord injuries the result of?
compression from tumor, hematoma or bony encroachment and from blunt trauma causing contusion of neural tissue
49
What are the 3 types of spinal injuries?
flexion, hyperextension (most common), and compression
50
SI/SX of spinal injuries
spinal shock, neurogenic shock (cervical or upper thoracic), hypertension, and bradycardia
51
Gullain-Barre Syndrome
inflammatory demyelinating disease of the PNS or a lower motor neuron disorder
52
SI/SX of Gullain- Barre Syndrome
progressive ascending weakness or paralysis beginning the lower extremities and spread to the proximal spinal neurons
53
What is the cause of Gullain-Barre?
idiopathic
54
Bell palsy
an acute idiopathc paresis or paralysis of the facial nerve involving an inflammatory rxn at or near the stylomastoid foramen or in the bony facial canal
55
What does Bell palsy have an occurrence with?
ischemia, compression and demyelination
56
SI/SX of bell palsy
unilateral facial weakness with facial droop and diminished eye blink, hyperacusis, and decreased lacrimation