Chemoreceptor Organ Pathology: Paragangliomas Flashcards by Zhenzhen George

Q

What are paragangliomas? (3)

A

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Q

Which dog breeds are predisposed to paragangliomas? (2)

A

The aetiology of carotid and aortic body tumours is unknown, but genetic predisposition aggravated by chronic hypoxia may account for the higher risk of certain brachycephalic breeds, such as the Boxer and Boston Terrier.
Chronic hypoxia - overstimulate chemoreceptor organs -> inc in tumours

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Q

Clinical signs displayed with paragangliomas (3)

A

Carotid and aortic bodies can initiate an increase in the depth, minute volume, and rate of respiration, as well as result in an increased heart rate and elevated arterial blood pressure.

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Q

What are paragangliomas composed of?

A

Parenchymal (chemoreceptor, glomus) cells and stellate (sustentacular) cells.

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Q

A

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Q

What are aortic body tumours? (4)

A

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Q

Aortic body adenoma and carcinoma gross pathology

A

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Q

Carotid body adenoma and carcinoma (3)

A

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Q

Carotid body adenoma and carcinoma gross pathology (3)

A

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Q

Paraganglioma histology and cytology

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Q

What are heart base tumours derived from? (3)

A

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Q

What are orbital (extra-adrenal) paragangliomas?

A

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Q

How are paragangliomas diagnosed? (4)

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Q

What are the top 3 differentials for heart base tumours in dogs?

A

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Q

What is the difference between chemodectomas and haemangiosarcoma on cytology?

A

Q

Which heart base tumour could result in right-sided congestive heart failure?

A

Aortic body adenoma

Q

Which heart base tumour could result in oesophageal dysfunction?

A

Carotid body adenoma

Q

Which heart base tumour is more likely to occur in pugs?

A

Aortic body carcinoma

Q

In which species are orbital paragangliomas commonly found?

A

Horse

Q

What is commonly used to diagnose a chemodectoma?

A

CT (computer tomography) scan