Chemical synapses

Question 1

What is convergance and divergance?

Answer 1

Convergance is multple cells converging onto one neuron.

Divergance is where info spreads to many other cells

Question 2

What are the steps in transmission

Answer 2

synthesis 
storage (in lipid bound membrane - vesicle)
Release
Postsynaptic effect
Inactivation

Question 3

What is meant by quantal release?

Answer 3

all vesicles contain standard size 30-50nm

Question 4

What are the 2 types on receptor on post synaptic neuron?

Answer 4

ligand gated ion channel (ionotrophic)

g-proteins coupled receptor (association with GTP binding protein)

Question 5

What can Ach bind to?

Answer 5

Nictotinic or muscurinic receptors

Question 6

What do G coupled receptors activate?

Answer 6

K+ channels

Question 7

What type of neurotransmitter are amino acids?

Answer 7

main excitatory transmitters in CNS (e.g.glutamate) they have both ionotrophic and gcouple receptors.

Question 8

What is main inhibitory neurotransmitter in CNS?

Answer 8

GABA

Question 9

What is main inhibitory neurotransmitter in spinal cord?

Answer 9

Glycine

Question 10

What can abnormalities in GABA cause?

Answer 10

Epilepsy or anxiety disorders

Question 11

WHat happens with neuropeptides?

Answer 11

are coreleased with other transmitters. can act conventionally or in neuromodulation.