Chapter Eighteen: Population Genetics Flashcards
…is the study of genes and genotypes in populations, and how they can change over time
Population Genetics
Population Genetics depends on the existence of genetic…
variation
….(many forms) refers to a trait that shows more than one phenotype
Polymorphism
To be considered polymorphic, rare alleles must be present at a frequency of >…
> 1%
Polymorphisms may be due to:
1. …of a region of a gene
2. …of a region of a gene
3. Change in a single… (substitution mutation) (Single-Nucleotide Polymorphism or snips)
Deletion
Duplication
nucleotide
snips represent …% of all variation in human DNA
90
To calculate allergic frequencies, it is necessary to know the…of all individuals in the population
genotypes
Equation for finding the frequency of allele:
of certain allele / #total allele
what two letters are typically used to symbolize two allelic frequencies?
p and q
…frequencies are the frequencies or proportions of the different genotypes
Genotypic
In 1908, what two people both independently proposed the conditions under which allelic and genotypic frequencies would remain constant (equilibrium)
Hardy and Weinberg
Under equilibrium, both allelic and genotypic frequencies would remain constant, and the genotypic frequencies would depend upon or could be calculated from what frequencies?
allelic frequencies
What are the five Hardy Weinberg Equilibrium Conditions?
- No mutations
- No natural selection
- No migration between populations
- Infinite population size
- Random Mating
Populations are…in Hardy-Weinberg Equilibrium and meet all 5 conditions for equilibrium
rarely
Hardy-Weinberg Equilibrium is useful to show the conditions under which allelic and genotypic frequencies will not remain constant but will…
Change
The change in allelic frequencies over time is…
microevolution