Chapter 8 Flashcards
The term “metabolism” includes which type(s) of cellular reactions?
Both anabolic and catabolic
Composed principally of amino acids, and acting as biological catalysts, ______ facilitate metabolic activities of the cell.
Ribosomes
Most enzymes are a functional type of ______ (a type of macromolecule)
Protein
An enzyme acts as a biological ______ that alters the rate of a reaction without being changed by the reaction.
Catalyst
Which statement is FALSE regarding enzymes?
Enzymes create reactions.
The combination of all reactions within a cell is termed ______.
Metabolism
The minimum amount of energy required for a reaction to proceed is termed the energy of ______.
Activation
Biological catalysts are known as
______.
Enzymes
Which best describes the function of enzymes?
Facilitate metabolic pathways
Enzymes typically lower the ______ energy needed for a reaction to proceed.
Activation
A specific molecule on which an enzyme acts is a(n) ______.
Substrate
Which of the following macromolecules can commonly act as catalysts?
Proteins
Typically, once an enzyme performs a “job”, it is ______.
Ready to “work” again
Although they do not create reactions, enzymes are indispensable for life because they:
Can speed up the rate of an uncatalyzed reaction by up to 100 trillion fold.
What term is used to describe the minimum amount of energy required for a reaction to proceed?
Activation energy
Specific types of RNA can function as nonenzyme ______.
Catalyst
Composed principally of amino acids, and acting as biological catalysts, ______ facilitate metabolic activities of the cell.
Enzymes
A non-functional enzyme which needs a cofactor is called a(n) ______.
Apoenzyme
Typically, the presence of enzymes ______ the activation energy needed for a reaction to proceed.
Lowers
A(n) ______ enzyme consists of protein alone, while a(n) ______ enzyme (or holoenzyme) consists of protein and nonprotein components.
Simple; conjugated
What name is given to the compound upon which an enzyme will act?
Substrate
Which of the following statements about enzymes are true?
Enzymes bind their substrate but are not changed in the reaction.
Enzymes are not consumed in the reaction they catalyze.
Enzymes lower the energy of activation for the reaction that they catalyze.
An enzyme with its apoenzyme and cofactors is referred to as a(n) ______, or a conjugated enzyme.
Holoenzyme
Certain types of the nucleic acid ______ can function as nonprotein enzymes.
RNA
What term refers to a biological catalyst that lacks an essential cofactor?
Apoenzyme
An enzyme with another molecule, such as a metal or vitamin cofactor, bound covalently to it is termed a(n) ______.
Conjugated enzyme
Which of the following is needed for an apoenzyme to be fully functional?
Cofactor
What can act as cofactors?
Metal ions
Coenzymes
Small organic molecules
Besides proteins, which type of molecule has been shown to have catalytic activity?
RNA
For an apoenzyme to become a functional holoenzyme, it must ______.
Bind to a cofactor
Protein folding determines the 3-D shape in enzymes needed for their______ for a particular substrate.
Specificity
The region on an enzyme that binds substrate is the ______ site.
Active, catalytic
An organic molecule or inorganic element that may be required for an enzyme to become functional is a(n) ______.
Cofactor
A region on an enzyme that is unique for each substrate is the ______ site.
Active, catalytic
Which model is sometimes used to describe enzyme-substrate interactions?
Lock-and-key
A complex organic molecule, often derived from vitamins, that acts in conjunction with an enzyme is known as a(n) ______.
Coenzyme
Which aspect of an enzyme’s structure gives rise to the specificity for its substrate?
Folding to produce a 3-D structure
Which of the options are names of major classes of enzymes?
Lyase
Hydrolase
Transferase
Which best defines an active site?
Region of an enzyme where the substrate binds
A catalyst composed of RNA is called a(n) ______.
Ribozyme
Which feature of an enzyme is the “most” unique?
Active site
Any enzyme that works outside a cell in which it was produced is a(n) ______.
Exoenzyme
Any enzyme that works within a cell in which it was produced is a(n) ______.
Endoenzyme
Compounds are called ______ when they can be easily denatured, distorted and/or degraded by mild changes to the environment.
Labile
What term is used to describe proteins losing their three dimensional structure as a consequence of changes in the environmental conditions such as excessive heat or salt?
Denaturation
Which of the following are classes of enzymes?
Transferases
Lyases
Isomerases