Chapter 52: Antienemic Therapy

Question 1

Promethazine
(Dopamine antagonist).

Answer 1

Type of medication: antihistamine & anticholinergic

Treats: nausea & vomiting by blocking D2 receptor to calm the nervous system. Sedating.

Side effects: sedation, confusion and disorientation

Important S/E: extrapyramidal symptoms, neuroleptic malignant syndrome

Black Box:
tissue necrosis w/ IV
Respiratory depression in children

Question 2

Ondansetron
(Serotonin antagonist)

Answer 2

Type of medication: serotonin antagonist that blocks 5-HT3 receptor in the stomach to prevent N/V.

Side effects: HA, diarrhea, poor blood flow of the heart.

Important S/E:
QT prolongation
Serotonin syndrome

Question 3

3 most common cause of increased iron demand:

Answer 3

Pregnancy.
Blood volume expansion infant to childhood.
Chronic blood loss.