Chapter 19: Adrenergic Antagonist Drugs

Question 1

Adrenergic Blockers

Answer 1

Bind to adrenergic receptors to block stimulation of sympathetic nervous system

Also known as: alpha blockers, beta blockers, or alpha-beta blockers

Question 2

Alpha Blockers: Mechanism of Action and Drug Effects

Answer 2

• cause both arterial and venous dilation, reducing BP
• used to treat hypertension
• decreases resistance to urinary flow, reducing urinary obstruction and relieve BPH.

Question 3

Alpha Blockers: indications

Answer 3

• used to control and prevent hypertension in patients with pheochromocytoma (adrenal gland tumor).
• Raynaud’s disease, acrocyanosis, and frostbite.
• Phentolamine: quickly reverses the vasoconstrictive effects of vasopressors such as Epinephrine and Norepinephrine

Question 4

Common Alpha Blockers

Answer 4

• Phenoxybenzamine HCL (Dibenzyline)
• Phentolamine
• Prazosin (minipress)
• Terazosin (Hytrin)
• Tamsulosin (flomax)
• Doxazosin (cardura)

Question 5

Which side effect of an Alpha-adrenergic antagonist drug would the nurse monitor for after the patient receives the first dose?

Answer 5

Syncope

Question 6

What is the therapeutic effect of an Alpha 1 blocker?

Answer 6

Increased in urinary output

Question 7

Which finding indicates that a patient is having an adverse effect of adrenergic drug therapy for hypertension?

Answer 7

Heart rate of 40 beats/min

Question 8

Anticholinergics

Answer 8

Ex: Atropine, Neostigmine,

Inhibit acetylcholine which blocks the chemical messenger that controls parasympathetic (rest and digest) nervous system.

Used to treat overactive bladder.

Side effects: dry mouth, blurry vision, dry eyes, constipation, urinary retention, dizziness.

Question 9

Cholinergic drugs mimic the effects of

Answer 9

Neutransmitter Acetylcholine

Question 10

Antidote for Anticholinergics

Answer 10

Physostigmine