Chapter 33: Adrenal Drugs Flashcards

1
Q

Short acting corticosteroids:

A
  1. Cortisone: orally only
  2. Hydrocortisone: orally, IV, IM & topical
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2
Q

Intermediate acting corticosteroids:

A
  1. Prednisone: orally only
  2. Prednisolone: oral, IV, topical
  3. Methylprednisolone: oral, IV, IM
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3
Q

Long acting corticosteroids:

A
  1. Betamethasone: oral, IV, IM
  2. Dexamethasone: oral, IV, IM, topical
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4
Q

Inhaled corticosteroids

A

These medications are only good for maintenance and prevention. Not for sudden acute treatment.

  • Fluticasone
  • Beclomethasone
  • Budesonide
  • Mometasone
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5
Q

Inhaled bronchodilator

A

Salmeterol & Albuterol provides immediate relief of symptoms by relaxing smooth muscles of airway

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6
Q

3 groups of Bronchodilators:

A
  • Beta 2 agonists
  • Anticholinergics
  • Methylxanthines

Provides bronchial smooth muscle relaxation, improved airflow.

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7
Q

Which inhaler is used for quick symptom relief in acute asthmatic attacks?

A

SABAs like Albuterol

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8
Q

Which inhaler is used for maintenance treatment for asthma or COPD?

A

LABAs (salmeterol) used w/ inhaled corticosteroid like Budesonide.

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9
Q

Inhaled Anticholinergics

A
  • ipratropium
  • tiotropium
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10
Q

Methylxanthines
(Theophylline)

A

Non inhaled drugs which treats asthma and COPD.

Available oral and IV only .

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11
Q

Theothylline toxic level

A

Occurs at levels greater than 20 mcg/ml

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12
Q

Glucocorticoids can cause ______ when taken systematically.

A

Hypokalemia.

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13
Q

Which medication is a mast cell stabilizer?

A

Cromolyn

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14
Q

Which pulmonary disease is characterized by enlargement of air spaces caused by destruction of the alveolar walls?

A

Emphysema

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15
Q

Inhaled ipratropium can cause ____.

A

Dry mouth

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16
Q

Which medication for asthma can suppress bone growth in children?

A

Corticosteroids

17
Q

Which drug is a long acting beta agonist (LABA) inhaler?

A

Salmeterol
Formoterol

18
Q

How long does it take for ipratropium to have its maximum effect?

A

1-2 hours

19
Q

Monteklukast is contraindicated with ______ allergy.

A

Lactose allergy

20
Q

Which medication disrupts inflammatory response and used for treatment of asthma?

A

Montekulast

21
Q

Adverse effects of albuterol

A

Tremors
Palpitations
Tachycardia

22
Q

Which medication used for asthma, is approved for children 1yr + and available for oral use only?

A

Montelukast

23
Q

Which thyroid condition causes moon face, acne, increased fat pads and swelling who is taking methylprednisolone?

A

Cushing’s syndrome

24
Q

Which drugs prevent inflammation provoked by mast cells?

A

Corticosteroids

25
Q

What is the frequency of inhalation of Salmeterol?

A

Inhale it twice a day, 12 hours apart

26
Q

Which lab parameter should be monitored while taking theophylline?

A

Serum level of the drug

27
Q

Which side effect of a Beta agonist bronchodilator needs to be reported to MD?

A

Tachycardia

28
Q

What is the correct way to administer albuterol and Beclomethasone inhalers?

A

Administer albuterol, wait 5 minutes, then administer beclomethasone

29
Q

What will be administered first to a patient with history of asthma who is wheezing and is hypoxic?

A

Beta2 agonist

30
Q

Taking rifampin with xanthine can cause ____.

A

theophylline levels are decreased

31
Q

What action can help improve absorption of tiotropium into the lungs?

A

Wait 1-2 minutes before inhaling second dose.

32
Q

What is the use for Zafirlukast (an antileukotriene agent)?

A

This medication will prevent the inflammation that causes your asthma attack.

33
Q

All steroid medications can cause these 4 side effects:

A
  1. GLUCOSE : increase in serum glucose
  2. INFECTION: masks the s/sx of infection, can lower your immune system.
  3. Highly ULCERATIVE: when taken on empty stomach can cause ulcers. advised to take with food, or with antacids
  4. POROUS BONES: can make bones brittle
34
Q
A