Chapter 36: Decongestant, Expectorant Therapy Flashcards

1
Q

Expectorants

A

Reduce thickness of secretions allowing for easy exit of mucus from respiratory tract. Used for common cold.

Example: Guaifenesin

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2
Q

Antitussives

A

Suppress harmful or nonproductive coughs.

Example: Codeine, Dextromethorphan

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3
Q

Mucolytics

A

Reacts directly to mucus to liquefy and loosen thick secretions, making cough more productive for expectoration.

Example: Acetylcysteine

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4
Q

Decongestants

A

Relieves nasal congestion.

Examples: Pseudoephedrine. Phenylephrine.

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5
Q

Which mechanisms do expectorants loosen respiratory secretions.

A
  • direct stimulation of secretory glands
  • reflex stimulation in response to irritation of GI tract
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6
Q

Describe the pharmacodynamics of Dextromethorphan.

A

Its onset is 15 to 30 minutes.

Both peak concentration and duration of action are 2.5 hours.

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7
Q

Which drug undergoes metabolism to form cysteine, disulfides and conjugates.

A

Acetylcysteine

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8
Q

How long does EX Pseudoephedrine last.

A

8 to 12 hours.

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9
Q

Dextromethorphan and Pseudoephedrine can worsen ________ .

A

Glaucoma

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10
Q

What is contraindicated with Pseudoephedrine?

A

Glaucoma
Hypertension
Hyperthyroidism

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11
Q

Pseudoephedrine starts working in _____

A

15 to 30 minutes

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12
Q

What is contraindicated with Acetylcysteine?

A

Patients with asthma, as inhaled Acetylcysteine could exacerbate respiratory symptoms.

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