Chapter 5 Flashcards

1
Q

integument

A

skin

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2
Q

what is the largest organ

A

skin

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3
Q

how large and thick is the skin

A

22 sq fit, 10-11 lbs, and 0.5-0.6 mm

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4
Q

what are the two layers of the skin

A

epidermis
dermis

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5
Q

what is the epidermis

A
  • superficial layer (epithelium of the skin)
  • stratified squamous epithelium
  • avascular
  • keratinized stratified squamous epithelium
  • composed of several layers
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6
Q

what are layers of the epidermis called

A

strata

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7
Q

what is the dermis

A

depper layer of areolar and dense irregular connective tissue

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8
Q

hypodermis

A

subcutaneous layer
not a part of the skin, but lies under the dermis and is composed of mostly adipose tissue

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9
Q

functions of the integument

A
  • Protection
  • Prevention of water loss
  • Temperature regulation
  • metabolic regulation
  • immue defense
  • sensory reception
  • excretion by means of secretion
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10
Q

epidermal strata

A
  • stratum basale
  • stratum spinosum
  • stratum granulosum
    stratum lucidum (found only in thick skin)
  • stratum corneum
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11
Q

what is the deepest strata called

A

stratum basale

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12
Q

what is the most superficial layer of state called

A

stratum corneum

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13
Q

stratum basale

A
  • single layer of cells that are capable of mitosis
  • the cells that are adjacent to the dermis
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14
Q

where do the multiplied cells go

A

they are pushed up and lose the ability to reproduce

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15
Q

what are the cells in the stratum basale

A
  • keratinocytes
  • melanocytes
  • tactile cells
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16
Q

keratinocytes

A
  • most abundant
  • produce keratin to protect and waterproof the skin
17
Q

melanocytes

A
  • cells that produce the pigment melanin
  • which absorbs UV light to prevent DNA damage
18
Q

tactile cells

A

cells sensitive to touch

19
Q

stratum spinosum

A
  • several layers thick of the reproduced cells from the stratum basale
  • differentiated into nondividing, highly specialized keratinocytes
20
Q

what are the cells present in the stratum spinosum

A

epidermal dendritic cells

21
Q

epidermal dendritic cells

A
  • immune cells that help fight infection
  • phagocytes that initiate an immune response
22
Q

stratum granulosum

A
  • 3-5 layers thick of keratinocytes
  • the cytoplasm fills with keratin filaments
  • organelles begin to degrade
  • fully keratinized cells are dead but strong
  • extracellular lipids form epidermal water barrier
23
Q

stratum lucidum

A
  • think, translucent region
  • 2-3 layers thick
  • present only in thick skin (palms, soles of the feet, places with no hair)
24
Q

descirbe the cells of the stratum lucidum

A
  • lack organelles
  • filled with eleidin: transparent, intermediate product of keratin maturation
25
Q

stratum corneum

A
  • most superficial layer of the epidermis
  • thickness varies from 20-30 layers depending on person and their activities
  • comprised solely of dead keratinocytes
26
Q

keratinization

A

cells formed on basal accumulate keratin as they are pushed up

27
Q

how long does keratinization take

A

about 5 weeks for a cell to be formed

28
Q

what does repeated abrasion do to the cells

A

will cause abnormal development and a thick stratum corneum to form