Chapter 4 Tissue Level Flashcards

1
Q

Epithelial tissue

A

Covers body surfaces and lines hollow organs, cavities, and ducts. Also forms glands.
Allows body to interact with internal and external environment
Is avascular.

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2
Q

Connective tissue

A

Protects and supports the body and its organs. Binds organs together, stores energy reserves, provides immunity

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3
Q

Muscular tissue

A

Composed of cells specialized for contraction and generation of force. Generates heat.

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4
Q

Nervous tissue

A

Detects changes inside and outside the body. Activates muscular contractions and glandular secretions.

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5
Q

Tight junctions

A

Transmembrane proteins that fuse the outer surfaces of adjacent plasma membranes. Seals off pathways between adjacent cells.
Inhibits passage between cells, prevent organ contents from leaking

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6
Q

Adhering junctions

A

Contain plaque. Attached to membrane proteins and microfilaments. Cadherins join the cells. Forms zones called adhesion belts.
Resists separations during contraction

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7
Q

Desmosomes

A

Contain plaque and cadherins. Attaches to intermediate filament. Prevent separation during contraction. Common among epidermis.

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8
Q

Hemidesmosomes

A

Do not link adjacent cells. Contains transmembrane glycoproteins called integrins.
Anchors cells to a basement membrane.

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9
Q

Gap junctions

A

Contains proteins called connexins. Form tunnels called connexons which allows passage of small molecules between different cells.
Common in nervous system, GI tract, uterus, heart.

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10
Q

Epithelial tissue cellular arrangements

A

Cells in continuous sheets in either single or multiple layers.
2 general types:
Surface epithelium
Glandular epithelium

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11
Q

Surface epithelium

A

Forms outer covering of skin and some internal organs. Forms inner lining of blood vessels, ducts, body cavities, respiratory, digestive, urinary, genital systems.

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12
Q

Glandular epithelium

A

Makes up secreting portion of glands, such as thyroid, adrenal, sweat, and digestive glands.

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13
Q

Apical surface

A

Faces the body surface, body cavity, lumen, or tubular duct that receives cell secretions.

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14
Q

Epithelial lateral surface

A

Faces adjacent cells on either side. May contain tight junction, adhering junction, desmosomes, or gap junctions.

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15
Q

Epithelial basal surface

A

Surfaces the deepest layer of epithelial cells. Adheres to extracellular materials such as basement membrane.

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16
Q

Basement membrane

A

Commonly consists of the basal lamina and the reticular lamina. Forms a surface for epithelial cells to migrate, restricts passage of larger molecules, participates in filtration.

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17
Q

Basal lamina

A

Closer to and secreted by epithelial cells. Adheres to integrins in hemidesmosomes and attaches epithelial cells to basement membrane.

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18
Q

Reticular lamina

A

Closer to underlying connective tissue. Contains collagen.

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19
Q

2 types of surface epithelial tissues

A

Simple epithelium
Stratified epithelium.

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20
Q

Simple epithelium

A

Single layer of cells functioning in secretion or absorption.
Simple squamous, cuboidal, columnar, psuedostratified.

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21
Q

Pseudostratified epithelium

A

Appears to have multiple layers of cells. Not all cells reach the apical surface. All cells rest on the basement membrane. May contain cilia or secrete mucus.

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22
Q

Stratified epithelium

A

2 or more layers of cells that protect underlying tissues.
Stratified squamous, cuboidal, columnar.

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23
Q

Epithelial cell shapes

A

Squamous
Cuboidal
Columnar
Transitional

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24
Q

Squamous epithelial cells

A

Thin cells which allow rapid passage of substances through them.

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25
Q

Cuboidal epithelial cells

A

Shaped like cubes or hexagons. May have microvilli. Function in secretion or absorption

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26
Q

Columnar epithelial cells

A

Taller than they are wide. Protect underlying tissues. May have cilia or microvilli. Specialized for secretion and absorption

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27
Q

Transitional epithelial cells

A

Change shape from squamous to cuboidal and back as organs distend and collapse.

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28
Q

Glandular epithelium

A

Secretes substances into ducts, onto a surface, or eventually into the blood.

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29
Q

Endocrine glands

A

Secrete hormones into interstitial fluid which diffuses into the blood without flowing through a duct.

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30
Q

Exocrine glands

A

Secrete products into ducts that empty onto an epithelium that covers or lines a surface.
Classified as unicellular or multicellular.

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31
Q

Unicellular glands

A

Single called glands. Goblet cells are most important unicellular glands which secrete mucus directly onto apical surface of a lining epithelium

32
Q

Multicellular glands

A

Composed of many cells that form a distinctive microscopic structure or macroscopic organ. Example includes sweat glands, sebaceous glands, salivary glands.

33
Q

Simple tubular multicellular glands

A

Secretory part is straight and attaches to a single unbranched duct.

34
Q

Simple branched tubular multicellular gland

A

Secretory part is branched and attaches to a single unbranched duct.

35
Q

Simple coiled tubular multicellular gland

A

Coiled and attaches to a single unbranched duct.

36
Q

Simple acinar multicellular gland

A

Secretory portion is rounded, attaches to a single unbranched duct.

37
Q

Simple branched acinar multicellular gland

A

Rounded secretory part branches and attaches to single unbranched duct.

38
Q

Compound tubular multicellular gland

A

Secretory portion is tubular and attached to a branched duct

39
Q

Compound acinar multicellular gland

A

Secretory portion is rounded and attached to a branched duct.

40
Q

Compound tubuloacinar multicellular gland

A

Secretory portion is both tubular and rounded and attached to a branched duct.

41
Q

Merocrine glands

A

Secretions are synthesized on ribosomes attached to rough ER. Processed, sorted, and packaged by Golgi and then released via exocytosis.

42
Q

Apocrine sweat glands

A

Accumulate secretory product at the apical surface of the secreting cell. Portion pinches off from rest of cell due to exocytosis. Cell repairs itself and repeats the process.

43
Q

Holocrine glands

A

Accumulate secretory product in cytosol. Cell ruptures as it matures and becomes the secretion.

44
Q

Extracellular matrix

A

Consists of protein fibres and ground substance.

45
Q

Connective tissue cells

A

Fibroblasts
Macrophages
Plasmocytes
Mast cells
Adipocytes
Leukocytes

46
Q

Ground substance

A

Connective tissue between cells and fibres. Supports cells, binds them together, stores water, provides a medium to exchange substances.

47
Q

Ground substance contents

A

Water, large molecules, glycosaminoglycans, proteoglycans.

48
Q

Hyaluronic acid

A

Viscous, slippery substance that binds cells together, lubricates joints, and helps maintain the shape of the eyeball.

49
Q

Chondroitin sulfate

A

Provides support and adhesion in cartilage, bone, skin, blood vessels

50
Q

Dermatan sulfate

A

Contained in skin, tendons, blood vessels, heart valves.

51
Q

Keratan sulfate

A

Present in bone, cartilage, and the cornea.

52
Q

Fibronectin

A

The main adhesion protein of connective tissues.

53
Q

3 main types of fibres in extracellular matrix

A

Collagen
Elastic
Reticular

54
Q

Collagen fibres

A

Very strong. Resist pulling or stretching. Allows for stretching.

55
Q

Elastic fibres

A

Form a fibrous network within connective tissue. Consist of elastin surrounded by fibrillin.
Strong and can be stretched. Returns to original shape.

56
Q

Reticular fibres

A

Consist of collagen arranged in fine bundles with a coating of glycoprotein. Provide support and strength.

57
Q

2 types of embryonic connective tissue

A

Mesenchyme
Mucoid.

58
Q

Mesenchyme

A

Present primarily in the embryo, developing from fertilization through the first 2 months of pregnancy.

59
Q

Mucoid connective tissue

A

Found in fetus. Develops from 3rd month of pregnancy.

60
Q

Connective tissue proper

A

Mature connective tissue. Flexible with viscous ground substance.
Loose connective tissue
Dense connective tissue.

61
Q

Supporting connective tissue

A

Mature. Includes cartilage and bone. Does not have blood supply.
Contains cells called chondrocytes.

62
Q

Perichondrium

A

Surrounds the surface of most cartilage and contains blood vessels, nerves, and is the source of new cartilage cells.

63
Q

3 types of cartilage

A

Hyaline
Fibrous
Elastic

64
Q

Interstitial growth

A

Growth from within the tissue. Chondrocytes divide, produce new matrix, and become pushed away from each other

65
Q

Appositional growth

A

Growth at the outer surface of the tissue. Cells at the inner layer of the perichondrium differentiate.

66
Q

Bone tissue

A

Stores calcium, phosphorus, house red bone marrow, yellow bone marrow.
Classified as either spongy or compact.

67
Q

Compact bone

A

Osteon system. Contains bone lamellae, lacunae, canaliculi, and osteonic canal.
Lamellae give bone hardness
Lacunae contain osteocytes
Canaliculi provide routes for nutrients
Osteonic canal contain blood vessel

68
Q

Spongy bone

A

Lacks osteons. Consists of bone trabeculae. Spaces between bone trabeculae contain red bone marrow.

69
Q

Blood tissue

A

Liquid connective tissue. Extracellular matrix called plasma.

70
Q

Lymph plasma

A

Lymphatic liquid connective tissue. Similar to blood plasma but contains less proteins.

71
Q

Mucous membranes

A

Mucosa. Lines a body cavity that opens directly to the exterior. Usually contains tight junctions. Lines lungs, urinary tract, digestive canal, genital tracts

72
Q

Lamina propria

A

Supports mucosa, binding it to underlying structures. Holds blood vessels in place, acts as vascular source for overlying epithelium.

73
Q

Serous membrane

A

Lines a body cavity that does not open directly to the exterior. Covers organs within a cavity. Consist of areolar connective tissue covered by mesothelium.

74
Q

Cutaneous membrane

A

Covers surface of the body. Consists of epidermis and dermis.

75
Q

Synovial membrane

A

Line the cavities of partially or freely moving joints. Lacks epithelium. Composed of synoviocytes which secrete synovial fluid.

76
Q

Tissue repair

A

Replacement of work out, damaged, or dead cells. Originate by cell division from the stroma (supporting connective tissue) or the parenchyma (functional part of the tissue).