Chapter 32 - Schizophrenia

Question 0

What neuropathology is observed in SZ?

Answer 0

Reduced dendritic complexity
Lower synapse density on pyramidal neurons
Reductions in gray matter volume
Decreased white matter integrity

Question 1

What do genetic models of SZ postulate are responsible for the heritable aspects of the disease?

Answer 1

Genes underlying neurodevelopment and brain maturation, along with those responsible for signal transduction, are responsible