Chapter 3 Flashcards
(1)Cell Metabolism
Sum of ALL chemical reactions;
Anabolic Reactions
Building reaction;
Small molecules bond to form big molecules (macromolecules)
Catabolic Reaction
Breaks down macromolecules into smaller molecules;
Oxidation-Reduction
Reactions convert energy in chemical bonds to ATP
(2)Transport
Substance the cell produced or ingested to different destinations ;
(3)Communication
Between cell itself, surrounding environment, and neighbor cells;
Uses chemical and electrical signals
(4)Cell Reproduction
Through cell division;
Necessary for :
- growth and development
- replacing old or damaged cells
Cell Structure
Animal cell;
Contains : plasma membrane, cytoplasm, and nucleus
Plasma Membrane
Surrounds each cell;
Isolates internal structures from outside;
Provides structural support, communication, and cell identification
Contains ICF
Cytoplasm
Consists of : (1) Cytosol (ICF), water with dissolved solutes, storage molecules & proteins;
(2) Organelles
(3) Cytoskeleton
Nucleus
Spherical shaped;
Enclosed in phospholipid bi-layer;
Contains most of cells DNA; (housing of and also containing the code/plan)
Location of RNA creation ;
Plasma Membrane Structure
~Phospholipid Bilayer ~
MUST HAVE:
- interactive parts with water in both fluid compartments, w/o falling apart
- repel water, keeping ECF and Cytosol separate
SELECTIVELY PERMEABLE
Phospholipids
Amphiphilic;
Face each fluid compartment (face to face)—Two fatty acids (tails) face one another
Passive Transport across membrane
DOESN’T require ENERGY to work
Random movement;
Concentration Gradient
Responsible for passive transport;
Molecules have kinetic energy (movement)
Diffusion
High to low concentration;
Moves DOWN until EQUILIBRIUM is reached
Simple Diffusion
Non polar ;
Pass through bilayer [without] membrane protein;
Example - oxygen, carbon dioxide, lipids, and hydrocarbons
Facilitated Diffusion
Polar solutes; (ions or glucose)
Cross bi layer with [help] of membrane protein;
Osmosis
Passive process;
Water moves lower solute across membrane to higher solute;
Water moves across membrane 2 ways:
- Channel proteins : Aquaporins
- Phospholipid Bi layer
At equilibrium what is the water concentration?
Concentration is EQUAL on either side of membrane; Gradient is gone
Tonicity
Compares osmotic pressure gradients; (Cytosol & ECF)
-ECF is Isotonic normally than Cytosol
same concentration
( no net movement of water )
( no volume change)
Hypertonic ECF
Cell shrinks; Crenates
Hypotonic ECF
Cell swells and can rupture ;
Example- water drinking contest
Organelle
Vital to maintaining homeostasis;
*Membrane bound *
Mitochondria , Peroxisomes, endoplasmic reticulum, Golgi apparatus, and lysosomes
Mitochondria
“Power Plant”
Proves majority of ATP;
*Folded into Cristae *
Peroxisomes
Produce H2O2 to :
-synthesize phospholipids
Membrane Bound
Ribosomes
Site of Protein synthesis; [make]
- Free in Cytosol
- Bound to membrane
Rough Endoplasmic Reticulum
(RER)
Ribosomes are attached
Smooth Endoplasmic Reticulum
(SER)
No ribosomes are attached
Rough E.R
Incorrectly folded polypeptide chains;
Protein enter for transport out
Smooth E.R
Stores calcium ions;
Detoxification reactions (limit damages)
Lipid synthesis
Golgi Apparatus
Between RER and plasma membrane; *Proteins and Lipids* *Modified, sorted, and packaged for export * Secreted (exocytosis) *Sent to lysosome*
Lysosomes
- Break -lyse *
* DIGEST & RECYCLE DAMAGED ORGANELLES*
Cytoskeleton
Internal framework;
- Provides strength*
- Cellular movement*
- Moter proteins*
- Functions : Phagocytosis or Contraction
Actin Filament
Thinnest filament;
Cellular motion with motor proteins [Myosis]
Intermediate filament
Rope like;
Fibrous proteins, includes [Keratin]
Functions:
Framework of cell;
Maintains shape & size
Withstand mechanical stress
Microtubules
Largest filament;
Composed of [Tubulin]
Functions:
Internal architecture
Transport of vesicles
Microvili
Finger like extensions;
Functions:
Increase surface area
Specialized for absorption
Cilia
Hair like;
Functions:
Move in unison
Found in great numbers
Flagella
Solitary;
Found in sperm cells
Function:
Propels entire cell
Mitosis
M phase;
Divides genetic material
Cell Theory
Cells [CAN’T] just appear;
DNA Synthesis
(Replication)
S phase;
Interphase
Period of growth & Prepares for cell division;
Nuclear envelope encloses nucleus-Centriole pairs duplicate-Nucleus & Nucleolus are visible;
Sub phases : G1 phase (1st gap performing production) G2 phase (2nd gap performing cellular growth)
Chromatin
One long DNA molecule with proteins;
Coils tightly into chromosomes;
Two sets of [23] chromosomes;
Prophase
Mitosis spindle forms;
Sister chromatids are joined at centromere
Metaphase
Spindle fibers from opposite poles of cells PULL sister chromatids into middle of cell
Anaphase
SISTER CHROMATIDS SEPARATE AND DAUGHTER CHROMOSOMES ARE PULLED TO OPPOSITE POLES OF CELL;
Telophase
Final stage
Chromosomes become Chromatin
*CYTOKINESIS OCCURS CONCURRENTLY
Cytokinesis
Creation of Daughter Cells
Functions:
1) Divides Cytosol & organelles between both daughter cells
2) Cell then splits apart as actin & myosin tighten around equator creating [Cleavage Furrow]
3) Separates into 2 genetically identical cells (Daughter Cells )
Fluid Mosaic Model
Plasma membrane that is a fluid structure containing multiple parts;
Integral Proteins
Entire membrane;
Transmembrane
Peripheral Proteins
Found only on one side of membrane or the other; Not both
Channels
Transmembrane proteins that allow specific substances to cross in or out of the cell
Carrier Proteins
Integral proteins that bind, change their shape, and directly transport substances in and out of the cell
Receptors
Bound to chemical messengers [Ligands]
Enzymes of the FMM
Speeds up chemical reaction;
Vital to maintaining homeostasis
Structural Support of FMM
Gives cell its shape after binding to cytoskeleton;
Link
Anchors cells together (within) tissues;
Allows cell to cell communication