Chapter 27: Medical Cannabis Flashcards
The cannabis plant is part of the ____________
Cannabaceae (aka hemp) - also includes hops & hackberry
The 2 must abundant phytocannabinoids in the cannabis plant are
Tetrahydrocannabinolic acid (THCA) & cannabidolic acid (CBDA)
The better known cannabinoids THC & CBD are derived from _____ phytocannabinoids
Heating
Federally, cannabis remains a Schedule 1 drug which means……
It’s thought to be highly addictive with no medicinal value
What are the 2 best studied cannabinoid receptors in the human body and where are they found?
CB1 - CNS
CB2 - peripheral & immune cells
Besides cannabinoids, the cannabis plant also contains ___________ (essential oil components) which have various benefits
Terpenoids
Define “entourage effect”
Synergistic effect when smoking the whole cannabis plant, as both terpenoids & cannabinoids are being consumed
These are the 2 single molecule synthetic THC products approved by the USDA by prescription
- Dronabinol
- Nabilone
Levonantradol is a synthetic cannibinoid only used in _______
Research (parenterally_)
Dronabinol is approved for treatment of (2):
- Chemo induced N/V refractory to standard treatment
- Anorexia-associated wt loss with aids
Nabilone is approved for (1):
CINVC
Research on cannabis for CINV
Very strong, more effective than many prescription anti-emetics, yet does well w/ moderate intensity chemos (not very high or very low emetogenic)
Research for cannabis on appetite w/ cancer
Not as strong as one would think, the research is limited
(may do better with using ad-lib than in a research setting)
Research for cannabis on taste/smell
“Food tastes better” but an extremely small study
Research for cannabis on pain
Becoming more common. Fewer side effects/toxicities than opioids.
Many studies have shown significant benefit
