Chapter 24 Exam Flashcards
examples of Gonadotropic hormones
FSH, LH, LTH
what does FSH do?
–Stimulates development of ovarian follicles in the female and sperm production in testes of the male
what does LH do?
– Works in conjunction with FSH to induce secretion of estrogen, ovulation, and development of corpus luteum
what does LTH do?
– Stimulates secretion of progesterone by the corpus luteum and secretion of milk by the mammary gland
Testosterone-
Secreted mainly in the interstitial tissue of the testes in the male and secondarily in the adrenal glands of both sexes
What is the DEA schedule/classification of non-combination androgens?
Schedule 3
Incidence of ED increases with-
– increases with age and chronic diseases
nitric oxide-
– principal mediator in attaining and maintaining an erection
What class of drugs has serious interactions with PDE inhibitors?-
– Nitrates or alpha-blockers (ex: Flomax, nitroglycerin) potentiates the hypotensive effects if used concurrently
Phosphodiesterase (PDE) Inhibitors def…
- Block phosphodiesterase type 5, found in the corpus cavernosum
- Thought to impair the production of nitric oxide
What is the risk of ET?-
– Associated with increased risk of endometrial carcinoma in women with an intact uterus
Progesterone is secreted by what?
the corpus luteum and adrenal glands
what is progesterone responsible for?
– Responsible for changes in uterine endometrium in the second half of the menstrual cycle
Example of changes in uterine endometrium
– In preparation for implantation, development of maternal placenta after implantation, and development of mammary glands
What birth control can be safely used if a woman is breastfeeding?
– Progestin-only contraceptives
How are estrogen-progestin oral contraceptives classified?-
– Classified according to estrogen content and formulation
Monophasic-
Each pill is designed to deliver the same level of hormone throughout the entire pill pack.
Progestin-only contraceptives are recommended for?
– Recommended for patients who do not tolerate estrogen or in whom it is contraindicated
Progestin-containing IUD-
– Releases small amounts of progesterone daily, providing five years of continuous contraception protection
example of Progestin-containing IUD-
– Mirena contains a reservoir of levonorgestrel, a synthetic progestin
Postcoital Contraception-
Morning after pills can be used after sex to stop a pregnancy before it starts.
Examples of postcoital contraception
– Next Choice – contains 2 tablets of the progestin levonorgestrel
– Lo/Ovral, Seasonale, Plan B One-Step, Ella
function of Oxytocics-
-hormone that stimulates the uterus to contract, thus inducing childbirth
– Also acts on the mammary gland to stimulate the release of milk
example of oxytocics
– oxytocin (Pitocin)
- prostaglandin E1 and E2
oxytocics def…
– Synthetic chemicals used to stimulate uterine contractions
– Goal of labor induction
facilitate vaginal delivery of a healthy infant
Magnesium Sulfate is used for….
– For prevention and control of seizures in eclamptic patients
preeclempsia is categorized by….
new-onset hypertension, edema, and proteinuria during pregnancy