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Pathology > Chapter 23 - The Breast > Flashcards

Chapter 23 - The Breast Flashcards

1
Q

All of the following are malignant tumors of the breast EXCEPT:

A. Phyllodes tumor
B. Angiosarcoma
C. DCIS
D. Fibroadenoma

A

D. Fibroadenoma

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2
Q

These result from the persistence of epidermal thickenings along the milk line.

A. Supernumerary nipples or breasts
B. Accessory axillary breast tissue
C. Congenital nipple inversion
D. None of the above

A

A. Supernumerary nipples or breasts

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3
Q

Which of the following is the most used screening test for breast cancer?

A. Breast ultrasound
B. Mammography
C. Sonomammography
D. MRI

A

B. Mammogram

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4
Q

All of the following are TRUE about acute mastitis EXCEPT:

A. Typically occurs during the 3rd month of breastfeeding
B. May be caused by P. aeruginosa
C. Erythematous and painless
D. Caused by widespread infection when most vulnerable to cracks and fissures
E. All of the above

A

E. All of the above

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5
Q

Which of the following is the key feature of squamous metaplasia of lactiferous ducts?

A. Painful erythematous subareolar mass
B. Nipple inversion due to traction produced by inflammation and scarring
C. Keratinizing squamous metaplasia
D. Double-layered cuboidal epithelium

A

C. Keratinizing squamous metaplasia

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6
Q

This condition presents as a palpable periareolar mass that is associated with thick, white nipple secretions but without pain and erythema

A. Fat necrosis
B. Periductal mastitis
C. Zuska disease
D. Duct ectasia

A

D. Duct ectasia

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7
Q

This condition presents as a painless palpable mass and may closely mimic cancer

A. Fat necrosis
B. Periductal mastitis
C. Zuska disease
D. Duct ectasia

A

A. Fat necrosis

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8
Q

This condition is most common in women with type 1 DM or autoimmune thyroid disease

A. Duct ectasia
B. Fat necrosis
C. Lymphocytic mastopathy
D. Granulomatous mastitis

A

C. Lymphocytic mastopathy

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9
Q

This condition occurs only in parous women

A. Sclerosing lymphocytic lobulitis
B. Granulomatous lobular mastitis
C. Cystic neutrophilic granulomatous mastitis
D. Recurrent subareolar abscess

A

B. Granulomatous lobular mastitis

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10
Q

All of the following are nonproliferative morphologic changes EXCEPT:

A. cystic change
B. fibrosis
C. adenosis
D. epithelial hyperplasia
E. None of the above
A

D. epithelial hyperplasia

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11
Q

All of the following has risk for subsequent carcinoma of the breast EXCEPT:

A. Fibrocystic breast changes
B. Proliferative breast disease without atypia
C. Proliferative breast disease with atypia
D. Carcinoma in situ
E. None of the above

A

A. Fibrocystic breast changes

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12
Q

All of the following are morphological patterns of proliferative breast disease without atypia EXCEPT:

A. epithelial hyperplasia
B. sclerosing adenosis
C. complex sclerosing lesion
D. papilloma
E. none of the above
A

E. none of the above

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13
Q

Gynecomastia belongs to which of the following?

A. Fibrocystic breast changes
B. Proliferative breast disease without atypia
C. Proliferative breast disease with atypia
D. Carcinoma in situ

A

B. Proliferative breast disease without atypia

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14
Q

All of the following are associated with development of gynecomastia EXCEPT:

A. alcohol
B. marijuana
C. heroin
D. catabolic steroid
E. None of the above
A

D. catabolic steroid

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15
Q

Which of the following has the absolute lifetime risk for developing invasive carcinoma?

A. Fibrocystic breast changes
B. Proliferative breast disease without atypia
C. Proliferative breast disease with atypia
D. Carcinoma in situ

A

D. Carcinoma in situ (25 to 30%)

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16
Q

All of the following are risk factors for developing breast cancer EXCEPT:

A. female gender
B. increasing age
C. germline mutations
D. early menarche
E. None of the options
A

E. None of the options

17
Q

Which of the following is responsible for familial breast cancers and has markedly increased risk for ovarian carcinoma?

A. BRCA1
B. BRCA2
C. ER
D. HER2
E. All of the above
A

A. BRCA1

18
Q

Luminal breast cancer refer to which of the following?

A. ER-positive; HER2-positive
B. ER-positive; HER2-negative
C. ER-negative;HER2-positive
D. ER-negative;HER2-negative

A

B. ER-positive; HER2-negative

19
Q

TNBC refers to which of the following?

A. ER-positive; HER2-positive
B. ER-positive; HER2-negative
C. ER-negative;HER2-positive
D. ER-negative;HER2-negative

A

D. ER-negative;HER2-negative

20
Q

Which of the following confers the highest percent of breast cancers?

A. Luminal A
B. Luminal B
C. HER2
D. TNBC

A

A. Luminal A

21
Q

Which of the following has the poorest prognosis?

A. Luminal A
B. Luminal B
C. HER2
D. TNBC

A

D. TNBC

Pathology (15 decks)

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