Chapter 23 Flashcards
What parts make up the urinary tract?
kidneys, ureters, bladder, urethra
What parts make up the male reproductive tract?
testes, epididymides, vas deferens, prostate gland, penis
What parts make up the female reproductive tract?
uterus, fallopian tubes, ovaries, vagina
What bacterial species make up the normal biota of the urinary tract?
Streptococci, Staphylococci, Corynebacteria, Lactobacilli, Prevotella, Veillonella, Gardernerella
What is cystitis?
Infection of the bladder
What is urethritis?
Infection limited to the urethra
What are the symptoms of cystitis?
pain, frequent urges to urinate even when bladder is empty, burning pain accompanying urination, cloudy urine, blood in the urine, low-grade fever, nausea
What are the indicators of pyelonephritis?
back pain and high fever accompanying UTI symptoms
What are the most common causes of community-acquired UTIs?
E. coli, Staphylococcus saprophyticus, Enterococcus
What are the most common causes of catheter-associated UTIs?
E. coli, S. saprophyticus, Enterococcus, Klebsiella
What drugs can be used to treat UTIs?
nitrofurantoin, phenazopyridine
what is leptospirosis?
a zoonosis that can affect the kidneys, liver, brain, and eyes
What are the two phases of leptospirosis?
leptospiremic phase and immune phase
What are the symptoms of leptospirosis in the leptospiremic phase?
sudden high fever, chills, headache, muscle aches, conjunctivitis, vomiting
What are the symptoms of leptospirosis in the immune phase?
milder fever, headache, Weil’s syndrome
What are the characteristics of leptospires?
spirochete bacteria marked by tight, regular, individual coils with a bend or hook at one or both ends
How is leptospirosis transmitted?
through contact of skin abrasions and mucous membranes with infected animal urine
How is leptospirosis treated?
Early treatment can be done with doxycycline; penicillin G of ceftriaxone can be used for delayed/severe cases
What are the symptoms of urinary schistomiasis?
itchiness in area where helminth entered body, fever, chills, diarrhea, cough, urinary tract infection symptoms
Which schistome causes urinary schistomiasis?
Schistosoma haematobium
What is vaginitis?
Inflammation of the vagina
What are the symptoms of vaginitis?
vaginal itching, burning, discharge
What is the most common causative agent of vaginitis?
Candida albicans
How is vaginitis treated?
topical and oral azole drugs
What are the symptoms of Trichomonas vaginalis?
vaginitis symptoms, white or green frothy discharge, premature labor, low-birthweight infants, infertility, prostate cancer in males
How is Trichomonas vaginalis transmitted?
sexual contact, communal bathing, public facilities, vertical transmission
How is Trichomonas vaginalis treated?
anti-protozoan drug metronidazole
What are the symptoms of vaginosis?
discharge, itching, fishy smell
What complications can result from vaginosis?
Pelvic inflammatory disease, infertility, ectopic pregnancies
What is the treatment for vaginosis?
oral or topical metronidazole or clindamycin
What is prostatitis?
inflammation of the prostate gland
what are the symptoms of prostatitis?
pain in the groin and lower back, frequent urge to urinate, difficulty urinating, blood in the urine, painful ejaculation; fever, chills, and flulike symptoms if acute
What is the treatment for prostatitis?
ciprofloxacin or levofloxacin
What is the causative agent of gonorrhea?
Neisseria gonorrhoeae
What are the symptoms of gonorrhea in males?
urethritis, painful urination and yellowish discharge, scar tissue that can cause infertility
What are the symptoms of gonorrhea in females?
mucopurulent or bloody vaginal discharge, painful urination
What complications of gonorrhea can occur in females?
Salpingitis (inflammation of fallopian tubes), pelvic inflammatory disease
How is gonorrhea transmitted?
Through sexual contact, or vertically from mother to infant
How is gonorrhea diagnosed?
PCR test, gram-staining
How is gonorrhea treated?
ceftriaxone and azithromycin; ertapenem for resistant strains
What are the symptoms of chlamydia in males?
urethritis, discharge, painful urination, epididymitis
What are the symptoms of chlamydia in females?
cervicitis, salpingitis, pelvic inflammatory disease
What is the causative agent of chlamydia?
C. trachomatis
How is chlamydia transmitted?
Through sexual contact and vertically
How is chlamydia diagnosed?
ELISA and PCR testing, direct fluorescent antibody testing, urine test, culturing
What treatment is used for chlamydia?
ceftriaxone or azithromycin
When is syphillis transmissible?
During the primary and secondary stages
What are the symptoms of primary syphillis?
appearance of hard chancre that begins as a small red bump that breaks down into a crater
What are the symptoms of secondary syphillis?
fever, headache, sore throat, lymphadenopathy, red/brown rash, hair loss
What are gummas?
painful, swollen, syphilitic tumors that develop during the tertiary stage of syphillis
What is the causative agent of syphillis?
Treponema pallidium
What are the characteristics of Treponema pallidium?
spirochete, thin, regularly coiled, gram-negative
How is syphilis diagnosed?
looking for bacterium in lesions or antibodies in patient’s blood
How can syphilis be prevented?
Prophylactic long-lasting penicillin for those exposed, barrier protection (i.e. condoms)
What treatment is used for syphilis?
Penicillin G
What is Chancroid?
an ulcerative disease marked by the development of a soft chancre and swelling of the inguinal lymph nodes
What is the causative agent of chancroid?
Haemophilus ducreyi
What treatment can be used for chancroid?
azithromycin and ceftriaxone
Which two viruses cause genital herpes?
Herpes simplex viruses 1 and 2
What are the symptoms of genital herpes?
vesicle appearance on the genitals, thighs, perineum, and buttocks; malaise; anorexia; fever; bilateral swelling and tenderness of the groin
Which HSV is associated with cold sores and fever blisters?
HSV-1
How are HSV 1 and 2 transmitted?
Direct contact with secretions containing the virus
How is genital herpes diagnosed?
Lesion appearance, PCR testing
Which drugs can be used to reduce viral shedding and decrease lesion frequency with genital herpes?
acyclovir, famciclovir, valacyclovir
What are the causative agents of genital wart diseases?
human papillomaviruses
What are the symptoms of human papillomaviruses?
Genital wart growths, ranging from small, flat bumps to cauliflower-like masses
What are the major virulence factors for cancer-causing HPVs?
Oncogenes
How are HPVs transmitted?
Direct contact, autoinoculation
How are HPVs diagnosed?
PCR-based screening tests
How can HPVs be prevented?
Gardisil vaccine, pap smear screening
What is Molluscum contagiosum?
a condition caused by an unidentified virus in the Poxviridae family that takes the form of skin lesions and can be transmitted sexually
When is Group B Streptococcus colonization a problem?
When pregnant women give birth vaginally without being treated for the colonization