Chapter 18: The endocrine system Flashcards
What is a hormone?
is a molecule that is released in one part of the body but regulates the activity of cells in other parts of the body.
How do hormones enter the blood?
Most hormones enter interstitial fluid and then the bloodstream.
What is an exocrine gland?
secrete their products into ducts that carry the secretions into body cavities
What is an endocrine gland?
secrete their products (hormones) into the interstitial fluid surrounding the secretory cells rather than into ducts
What do molecules do in the endocrine system?
Hormones delivered to tissues throughout body by blood.
What does site of action mean in the endocrine system?
Far from site of release (usually); binds to receptors on or in target cells.
What type of target cells are associated with the endocrine system?
Cells throughout the body.
What does time to onset of action in the endocrine system mean?
Seconds to hours or days
What is the duration of action for the endocrine system?
generally longer (seconds to days)
Hormones influence target cells by binding to a specific protein ____________
receptors
Only the _________ cells for a given hormone have
receptors that bind and recognize that hormone
target
What is the down-regulation of target cell receptors?
When there is an excess of target cells receptors in the blood so the body decreases the sensitivity of the receptors
What is the up-regulation of target cell receptors?
When there is less of target cells receptors in the blood so the body icreases the sensitivity of the receptors
Most endocrine hormones are _________hormones—they pass from the secretory cells that make them into interstitial fluid and then into the blood
circulating
What is a local hormone?
They act only on neighboring cells