Chapter 17 Flashcards

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1
Q

Vascular interface between the blood vessels
serving the brain and the brain its self that prohibits
most microorganisms and most antibiotics from
entering the nervous system

A

Blood-brain barrier

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2
Q

Phagocytic cells found exclusively in the brain

A

Microglia cells

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3
Q

Are there normal biota within the nervous system?

A

No. it is a sterile environment

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4
Q

Inflammation of the meninges

A

Meningitis

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5
Q

Causes the most serious form of acute meningitis

A

Neisseria meningitidis

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6
Q

Headache,Painful or stiff neck,Fever Nausea and
vomiting,Photophobia (sensitivity to light),Skin
rashes are all signs/symptoms of

A

Meningitis

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7
Q

A rash associated with a Neisseria meningitides

infection

A

Petechiae

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8
Q

Acute enteroviral infection of the spinal cord that

can cause neuromuscular paralysis.

A

Poliomyelitis

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9
Q

How is the polio virus spread?

A

Fecal-oral transmission

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10
Q

What happens in Non-paralytic Polio?

A

Invasion, but not destruction of, nervous
tissue.Muscle pain and spasm, meningeal
inflammation, and vague hypersensitivity

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11
Q

What happens in Paralytic Polio?

A

Invasion of motor neurons causes flaccid paralysis.
Paralysis of the muscles of the legs, abdomen,
back, diaphragm, pectoral girdle, and bladder can
result.

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12
Q

Misfolded proteins known to cause
Neurodegenerative diseases with long incubation
periods but rapid progressions

A

Prions

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13
Q

Prions are known to cause

A

Creutzfeldt-Jakob disease (CJD)

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14
Q

How is rabies spread?

A

Primarily saliva

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15
Q

Incubation period for rabies is 1 – 2 months or

more, depending on:

A

the wound site in relation to the brain, severity of the wound, and inoculation dose.

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16
Q

Delirium, hallucinations, hydrophobia, muscle
spasms, coma and death are all signs/symptoms
of____

A

Rabies

17
Q

When must rabies be treated?

A

before signs and symptoms begin

18
Q

How is a rabies infection treated? (assuming its before signs and symptoms begin)

A

Wound is infused with human rabies immune
globulin to impede spread of the virus. A full
course of vaccine is begun as well.

19
Q

Caused by Clostridium tetani

A

Tetanus

20
Q

Powerful neurotoxin released by C. tetani

A

Tetanospasmin

21
Q

Tetanospasmin functions to:

A

block the inhibition of muscle contraction, causing

muscles to contract uncontrollably

22
Q

Causative agent of Botulism

A

Clostridium botulinum

23
Q

How is Clostridium botulinum transmitted

A
Predominately through the ingestion of
contaminated food (canned vegetables)
24
Q

Where can Clostridium tetani be found?

A

the soil

25
Q

Action of the botulinum toxin:

A

Prevents the release of acetylcholine, the
neurotransmitter that initiates the signal for muscle
contraction. Causes muscle paralysis

26
Q

Babies born with abnormally small heads

A

Microcephaly

27
Q

Transmitted by the bite of a mosquito, via sexual intercourse with infected individuals, and vertically in utero

A

Zika virus

28
Q

Commonly through Accidental puncture wounds

A

Tetanus