Chapter 11 Flashcards
The disruption of a tissue or organ caused by
microbes or their products.
Infectious Disease
Microorganisms that live in or on the human
body and do not cause any harm
Normal Biota
The generally antagonistic effect “good” microbes
have against intruder microorganisms
Microbial Antagonism
A microbe whose relationship with its host is
parasitic and results in infection and disease.
Pathogen
Pathogens capable of causing disease in healthy
persons with normal immune defenses.
True pathogens
__________________ cause disease when
the host defenses are compromised or when they
becomes established in a part of the body is not
natural to the microganism
Opportunistic Pathogens
The severity of the disease caused by the microbe.
Virulence
A type of virulence factor used to avoid phagocyte cells
Antiphagocytic factors
Toxins produced by bacteria that are deadly to
WBCs
Leukocidins
White blood cells that engulf and destroy
pathogens by means of antimicrobial chemicals
and enzymes
Phagocytes
A bacterial enzyme that accelerates the coagulation
(blood clotting) of blood
Coagulase
Bacterial enzyme that dissolves blood clots.
Kinase
Enzymes produced by gram positive bacteria. Are
soluble substances secreted into host tissue
Exotoxins
Are part of the cell wall lipopolysaccharide and are
released into host tissues from gram negative
bacteria often when bacteria die or divide.
Endotoxins
Exotoxins known to lyse red blood cells
Hemolysins
Exotoxins that act on tissues of the nervous system
to prevent muscle contraction or muscle relaxation
Neurotoxins