Chapter 17 Flashcards
Upper Respiratory Tract
Mouth, pharynx, larynx
Lower Respiratory Tract
trachea, 2 primary bronchi, branches, lungs
Alveoli
site of gas exchange
Pleural Sacs
surround each lung
Pleural Fluid
Lowers friction between membranes, golds lungs tight against the thoracic wall
Lung Anatomy
Apex (top), superior lobe, middle lobe, inferior lobe, cardiac notch, base
Muscles of Inspiration
External Intercostals, Diaphragm
Muscles of Expiration
Internal Intercostals, Abdominal Muscles
Type I alveolar cell
gas exchange
Type II alveolar cell
surfactant cell, synthesizes surfactant
Conducting System
trachea, primary bronchi, smaller bronchi, bronchioles
Exchange Surface
Respiratory bronchioles, alveoli
Larynx
contains vocal cords
Airways
warm air to body temperature, humidify by adding water vapor, filter inspired air
Connective tissue
elastin/collagen
Goblet cell
secretes mucus
Mucus layer
traps inhaled particles
CFTR
allow Cl- to enter the lumen (cystic fibrosis transmembrane regulator channel)
NKCC
brings Cl- into epithelial cell from ECF
Dalton’s law
total pressure equals sum of all partial pressures (Pgas)
Boyle’s law
pressure-volume relationships (P1V1=P2V2), inverse relationship between pressure and volume
Ideal Gas Equation in the Body
V = 1/P
Tidal Volume
volume that moves during a respiratory cycle
Inspiratory Reserve Volume
additional volume above tidal volume
Expiratory Reserve Volume
Forcefully exhaled after the end of a normal expiration
Residual Volume
volume of air in the respiratory system after maximal exhalation
Vital Capacity
IRV + ERV + Vt
TLC
IRV + ERV + Vt + RV
The Spirometer
When the subject inhales, air moves into the lungs, the volume of the bell decreases, and the pen rises on the tracing
Surfactants
disrupts cohesive force of water, mixture containing proteins and phospholipids, more concentrated in smaller alveoli
Premature Babies
inadequate surfactant concentrations, NRDS
Law of LaPLace
P = 2T/r
Hyperpnea
increased respiratory rate and or volume in response to increased metabolism
Hyperventilation
increased respiratory rate and or volume without increased metabolism
Hypoventilation
decreased alveolar ventilation, asthma
Tachypnea
rapid breathing, usually increased respiratory rate with decreased depth, panting
Dyspnea
difficulty breathing
Apnea
cessation of breathing
Obstructive Lung Disease
increase airway resistance, asthma, COPD
Restrictive Lung Disease
reduced long compliance, pulmonary fibrosis