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Physiology > Chapter 12 > Flashcards

Chapter 12 Flashcards

1
Q

Skeletal Muscle

A

striated, voluntary, multinucleated

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2
Q

Cardiac Muscle

A

striated, intercalated disks, involuntary, branched

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3
Q

Smooth Muscle

A

unstriated, involuntary, single nucleated

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4
Q

Structure of Skeletal Muscle

A

Fascicles -> Fibers -> Sarcoplasm -> Myofibrils -> Sarcomere

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5
Q

Myofibrils

A

troponin, actin, tropomyosin, myosin, titin, nebulin

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6
Q

Sarcoplasm

A

Sarcoplasmic reticulum, myofibrils, mitochondria, glycogen granules

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7
Q

Sarcolemma

A

Cell Membrane

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8
Q

Sarcoplasm

A

Cytoplasm

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9
Q

Sarcoplasmic Reticulum

A

Endoplasmic Reticulum, Longitudinal tubes with enlarged ends called terminal cisternae, concentrates and sequesters Ca2+

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10
Q

Regulatory Proteins

A

Tropomyosin, Troponin

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11
Q

Accessory Proteins

A

Titin, Nebulin

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12
Q

Nebulin

A

actin builds around

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13
Q

Tropomyosin

A

wraps around actin, blocks from myosin

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14
Q

Troponin

A

binds tropomyosin to G-actin, 3 parts

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15
Q

T-tubules

A

extension of the cell membrane that is associated with the ends of the sarcoplasmic reticulum

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16
Q

Detachment

A

ATP binds and myosin detaches, ATP decreases myosin affinity for actin

17
Q

Recocking

A

ATP hydrolysis provides energy for the myosin head to rotate and reattach actin

18
Q

Power Stroke

A
  1. Response to Ca2+ binding to troponin
  2. Release of Pi allows the head to swivel
19
Q

Rigor State

A

occurs when no ATP/ADP is bound to myosin

20
Q

ACh

A

initiates an action potential in the muscle fiiber, binds ot receptors on the sarcolemma, Na2+ enters the cell and K+ ions exits the cell, Depolarization event

21
Q

L-type calcium channel (DHP)

A

receptor on t-tubule

22
Q

Ryanodine Receptors (RyR)

A

sarcoplasmic reticulum

Physiology (21 decks)

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