Chapter 13: nervous system medications Flashcards

1
Q

key terms

A
  • adrenergy (sympathomimetics)
  • analgesic
  • anxiolytic
  • aura
  • autonomic nervous system
  • blood brain barrier
  • central n3ervous system
  • cholinergic (parasympathomimetic)
  • drug holiday
  • gamma aminobutyric acid
  • hydantoins
  • monoamine oxidase inhibitors
  • narcotic
  • neuroleptic
  • neurotransmitters
  • parasympathetic
  • peripheral nervous system
  • psychotropic
  • selective serotonin reuptake inhibitors
  • somatic nervous system
  • status epilepticus
  • sympathetic nervous system
  • synapse
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2
Q

nervous system: divided into

A

central nervous system
peripheral nervous system

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3
Q

central nervous system

A

brain and spinal cord

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4
Q

peripheral nervous system

A

includes somatic and autonomic nervous system

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5
Q

nervous system medications: used to treat

A
  • pain
  • anxiety
  • depression
  • mania
  • insomnia
  • convulsions
  • schizophrenia
  • pschotropics
  • acts on CNS and PNS
  • mot act at synapse between nerves to adjust transmission of messages by neurotransmitters
  • most cross blood brain barrier: serious side effects
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6
Q

peripheral nervous system

A

somatic nervous system
autonomic nervous system

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7
Q

somatic nervous system

A

voluntary
- muscles we have conscious control over

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8
Q

autonomic nervous system (involuntary)

A

controls internal organs
- broken down into sympathetic nervous system and parasympathetic nervous system

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9
Q

sympathetic nervous system

A

controls fight or flight response

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10
Q

parasympathetic nervous system

A

helps body to rest and relax

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11
Q

autonomic nervous system

A

cholinergic
adrenergic

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12
Q

cholinergic

A

nerve cell that releases acetylcholine, which relaxes the body

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13
Q

adrenergic

A

nerve cell that releases epinephrine or norepinephrine, which excites the body

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14
Q

both cholinergic or adrenergic are

A

naturally occurring substances
- if not adequate to met the body’s needs, artificial equivalents provided through medication

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15
Q

sympathomimetics

A
  • mimic the sympathetic system
  • used when body needs to be excited; mimic sympathetic nervous system
  • stimulates fight or flight response
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16
Q

fight or flight response

A
  • restore heart rhythm during cardiac arrest
  • increase blood pressure during shock
  • constrict capillaries if pt is bleeding
  • dilate bronchioles of asthmatic
  • dilate pupils for eye procedures
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17
Q

contraindications with sympathomimetics

A

hypersensitivity

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18
Q

sympathomimetics

A
  • hypertension
  • myocardial infarction
  • atrial fibrillation
  • hypovolemia
  • children
  • pregnancy
  • breastfeeding
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19
Q

examples of sympathomimetics

A

levophed
epinephrine

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20
Q

adrenergic blockers

A
  • block the action of adrenergics
  • parasympathetic effet
  • used to calm (slow heart rate, relax blood vessels)
    treat cardiac arrhythmias
  • high blood pressure
  • migraine headaches
  • chest pain
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21
Q

adrenergic blocks are broken into two groups based on muscles affected

A

alpha blockers
beta blockers

22
Q

alpha blockers

A
  • affect vascular smooth muscle
  • treat hypertension and BPH
23
Q

beta blockers

A
  • block epinephrine
  • slow heart rate and force
  • treat hypertension, migraines, glaucoma
24
Q

parasympathomimetics

A
  • mimic parasympathetic system
  • release acetylcholine, which relaxes fight or flight mechanism
  • rarely used due to sevre decrease in heart rate, constriction of respiratory passages
  • ex: nerve gas, pilocarpine used to treat open angle glaucoma
25
Q

anticholinergics

A
  • inhibit parasympathetic nervous system
  • promote fight or flight symptoms
  • dry secretions
  • used to treat asthma, motion sickness, preoperative relasxation, neuromuscular blocking of spasms, antidotes for insect stings, cholinergic risis
  • example: atropine
26
Q

medications to control pain and fever

A

analgesics

27
Q

analgesics

A

reduce pain without eliminating feeling or sensation
- choices include salicylates, acetaminophen, NSAIDs, and narcotics
- some of these drugs are also antipyretic (fever reducing)

28
Q

salicylates

A
  • relieve mild to moderate pain
  • reduce inflammation and fever
  • examples: aspiin, methylsalsicylate (bengay)
29
Q

aspirin

A

causes GI distress
not to be used in children

30
Q

methylsalicylate (bengay)

A

topical anti inflammatory used to irritate surface of skin which increases blood flow, thus decreases pain

31
Q

acetaminophen

A
  • decreases pain and fever
  • no anti inflammatory effect
  • contained in many combination products: e.g. cold medictions
  • combined w/ narcotics to treatr moderate to severe pain: oxoycodone with acetaminophen (percocet)
32
Q

nonsteroidal anti inflammatory drugs

A
  • reduce pain, inflammation, fever
  • ex: ibuprofen
    0 may be combined with narcotics to relieve moderate to severe pain
  • oxycodone with ibuprofen (combunox)
33
Q

opioid analgesics

A
  • strong pain killers
  • suppress the cns
  • active ingredient inmost narcotics is opium
  • excess can cause decreased bp, this may lead to risk of falls or death
  • decrease in respirations
  • examples: morphine, codeine, fentanyl
  • addiction potential w/ long term use due to feeligns of euphoria
  • severe side effects: slowed respirations, decreased bp
34
Q

medications to treat anxiey, insomnia, sedation, and seixures

A
  • limbic system of brain: integral to emotions, memory, level of alertness
35
Q

if the structures in the limbic system are not operating optimally, the following may occur

A

anxiety
sleeplessness
alertness
seizures

36
Q

anxiolytic medications

A
  • reduce intensity of fears, dangers, and/or tension
  • calming effect from mild sedation to coma
37
Q

CNS depressants

A

type of anxiolytic used to treat anxiety and restlessness
- benzodiazepines: treat anxiety, seizures, alcohol withdrawal symptoms and muscle relaxation: lorazepam, diazepam, alprazola
- barbiturates: phenobarbitol

38
Q

anxiolytics: SSRIs

A

citalopram
fluoxetine
sertraline

39
Q

anxiolytics: SNRIs

A

venlafaxine
tricyclic antidepressants: amitriptyline
- do not work s quickly, but few dependence issues

40
Q

insomnia and medications

A
  • barbiturates induce sleep by depressing CNS
41
Q

non narcotic benzodiazepine hypnotics

A
  • zolpidem
  • eszopiolone
  • few side effects (do not affect entire CNS)
  • possible addiction risk
42
Q

bartiturates and antiseizure medications

A

hydanoins
barbiturates
succinimides

43
Q

hydantoins

A
  • phenytoin (Dilantin)
  • delay sodium from crossing neural membranes, calming cells
  • drug of choice for tonic clonic and partial seizures
44
Q

barbiturates

A
  • phenobarbital
  • used for tonic clonic and febrile seizures
45
Q

succinimides

A
  • ethosuximide (zarontin)
  • delay clcium moving over neurons to relax nerve cells
  • drug of choice for absence (petit mal) seizures
46
Q

gamma amino butyric acid (GABA)

A
  • naturally occurring neurotransmitter inhibitor
  • increased presence decreases seizure activity
  • ex: vigabatrin (sabril)
47
Q

benzodiazepines such as ____ intensity effect of gaba transmitters in brain

A
  • valium
48
Q

other anti seizure medication

A

lamictal
gabitril
topamax
tegretol

49
Q

some medications

A
  • reduce seizures managing alcohol withdrawal symptoms by reducing anxiety symptoms (librum)
50
Q
A