Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Systems Path Exam II > Chapter 11 Part I > Flashcards

Chapter 11 Part I Flashcards

1
Q

RBCs are AKA

A

erythrocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

WBCs are AKA

A

leukocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

formation and development of blood cells, hematology

A

hematopoiesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

the production, function and destruction of one type of cell (RBC or WBC) are usually closely linked and affect one another… therefore they are ______

A

interconnected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

formation or development of blood cells in liver, spleen, lymph nodes and thymus

A

extramedullary hematopoiesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

hematopoiesis is more common in the VERTEBRAE and pelvis ______ in life

A

older

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

rupture of erythrocytes; releases contents in hemoglobin

A

hemolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

erythrocyte production in red bone marrow; compensatory hyperplasia of RBC stem cells

A

erythropoiesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

immature RBCs; mature 1 day in circulation

A

reticulocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

marrow failure, decrease circulating reticulocytes

A

reticulocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

increase in RBCs

A

polycythemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

with anemia, there is a DECREASE in RBC _____ and DECREASE in _____ capacity

A

mass

oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

___% of men and ___% of women have anemia in US

A

4%

8%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

(3) causes of anemia

A 
blood loss (hemorrhage)
increase RBC destruction
decrease RBC production
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

anemia produces tissues _____ which leads to ____ oxygen supply

A

hypoxia

decrease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

recovery from anemia is enhanced by compensatory rise in ____ level which stimulates ____ RBC production and renal fibroblasts by _____ times

A

erythropoietin
increase
5-8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

RBC morphology is associated with cause; (3) categories

A

microcytic (small)
normocytic (decrease #)
macrocytic (enlarged)

18
Q 
pallor
fatique
weakness (LASSITUDE)
decrease growth
osseous abnormalities
cachexia
associated with:
A

anemia

19
Q

hemolytic: Hb –> bilirubin –> ________

A

jaundice/gallstones

20
Q

the severity of anemia depends on (2)

A

rate of onset

mechanism

21
Q

anemia of blood loss is AKA _______ ; caused by burns, internal injuries (GI), diarrhea, gyno

A

hemorrhagic anemia

22
Q

hemorrhagic anemia has risk of ________ if more than 20% blood volume –> end organ failure

A

hypovolemic shock

23
Q

the RBCs in hemorrhagic anemia are considered ____ & ______

A

normocytic

normochromic

24
Q

renal hypoxia –> ____ in EPO, hemodilution: in ___ days; reticulocytosis in ______ days

A

increase
2-3 days
5-7 days

25
Q

___ is needed for hemoglobin synthesis, chronic blood loss –> ___ stores of ____

A

iron

decrease stores of iron

26
Q

accelerated RBC destruction occurs in ____ anemia

A

hemolytic

27
Q

normal RBCs have lifespan of ____ days; in hemolytic anemia, RBCs have lifespan of ____ days

A

120

15-20 days

28
Q

hemolytic anemia that is hereditary; enzyme deficiency, disordered Hb synthesis

A

intracorpuscular defects

29
Q

hemolytic anemia that is acquired: antibodies, RBC trauma, infections

A

extracorpuscular defects

30
Q

MC category of hemolytic anemia

A

extravascular

31
Q

hemolytic anemia with trauma to RBC membrane, physical/biochemical; damaged heart valve, toxins, heat, complement, hemoglobinura

A

intravascular hemolysis

32
Q

hemoglobin in urine

A

hemoglobinuria

33
Q

hemolytic anemia with macrophages in spleen, liver – blood leaves circulation and ends up in an organ

A

extravascular hemolysis

34
Q

extravascular hemolysis – RBCs usually end up in which organs

A

SPLEEN = MC

liver

35
Q

abnormally shaped RBCs, general term

A

poikilocyte

36
Q

irregularly shaped RBCs, from hemolysis (helmet shaped)

A

schistocyte

37
Q

teardrop-shaped RBC

A

darcocyte

38
Q

types of hemolytic anemia (8)

A 
hereditary spherocytosis
sickle cell anemia
thalassemia
glucose 6-phosphate dehydrogenase deficiency
paroxysmal nocturnal hemoglobinuria
immunohemolytic anemias
traumatic
malaria
39
Q

Hereditary spherocytosis is an autosomal _____ mutation and _____ defect, abnormal _______ membrane, fragile

A

dominant
intracorpuscular
RBC membrane

40
Q

RBCs are LESS elastic which leads to shedding in ______

A

hereditary spherocytosis

41
Q

(2) characteristics of hereditary spherocytosis

A

spherocytes (sphere shaped)

decrease life span (removed by SPLEEN)

42
Q

treatment for hereditary spherocytosis is

A

splenectomy

Systems Path Exam II (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions