Chapter 11 - Memory, Learning, Amnesia Flashcards

1
Q

On which memory test did H.M. display deficits?
A. mirror-drawing test
B. Pavlovian conditioning
C. block-tapping test
D. incomplete-pictures test

A

c

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2
Q

H.M.’s case showed us that:
A. there is a difference between implicit and explicit forms of memory.
B. Pavlovian conditioning is a form of explicit memory.
C. the amygdala is involved in explicit memory.
D. the digit span + 1 test is a test of implicit memory

A

a

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3
Q

Repetition priming tests are tests of _____ memory.
A. working
B. explicit
C. declarative
D. implicit

A

d

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4
Q

__________ memories are memories for general facts or information, whereas ______________ memories are memories for the particular events.
A. Explicit; implicit
B. Implicit; explicit
C. Semantic; episodic
D. Episodic; semantic

A

c

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5
Q

In transient global amnesia, there is:
A. almost always severe retrograde amnesia for implicit memories.
B. virtually always anterograde amnesia for explicit memories.
C. always permanent, diffuse brain damage.
D. often a slow, insidious onset.

A

b

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6
Q

Korsakoff’s syndrome is a disorder of memory common in people who have:
A. Alzheimer’s disease.
B. consumed large amounts of alcohol.
C. had bilateral medial temporal lobectomies.
D. consumed too much thiamine.

A

b

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7
Q

Evidence indicates that the brain damage associated with Korsakoff’s syndrome is at least partially due to:
A. too little acetylcholine.
B. iron deficiency.
C. too much acetylcholine.
D. thiamine deficiency.

A

d

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8
Q

In some respects, the memory deficits associated with Korsakoff’s syndrome are similar to those found in:
A. Alzheimer’s disease.
B. diffuse damage to the amygdala.
C. transient epileptic amnesia.
D. medial temporal lobe amnesia.

A

d

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9
Q

The first sign of Alzheimer’s disease is often:
A. a mild loss of bladder control.
B. a severe loss of memory.
C. excessive alcohol and drug use.
D. mild memory impairments.

A

d

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10
Q

The level of acetylcholine is often reduced in the brains of Alzheimer’s patients. This reduction likely results from the degeneration of cells in the:
A. amygdala.
B. basal forebrain.
C. mediodorsal nuclei of the thalamus.
D. hippocampus.

A

b

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11
Q

Testing of victims of cerebral trauma indicates that:
A. closed-head traumatic brain injuries preferentially disrupt older memories.
B. memory consolidation is not a viable theory.
C. lasting memories deteriorate and become more vulnerable to disruption.
D. lasting memories become linked to additional memories and more resistant to disruption.

A

d

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12
Q

Hebb argued that memories of experiences are stored in the short term by:
A. the mediodorsal nuclei of the thalamus.
B. the basal forebrain.
C. neural activity reverberating in closed circuits.
D. the cortex.

A

c

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13
Q

To account for the fact that H.M.’s bilateral medial temporal lobectomy produced retrograde amnesia only for those events that occurred in the few years just before his surgery, it was suggested that memories are temporarily stored in the hippocampus until they can be transferred to a more stable cortical store. This theory became known as _____ theory.
A. Hebb’s reconsolidation
B. the multiple-trace
C. the hippocampal-cortical
D. the standard consolidation

A

d

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14
Q

A change in the brain that stores memory is known as:
A. reconsolidation.
B. an engram.
C. a penumbra.
D. an infarct.

A

b

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15
Q

The _____________________ hypothesis holds that each time a memory is retrieved from long-term storage, it becomes labile.
A. consolidation
B. engram
C. reconsolidation
D. global amnesia

A

c

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16
Q

In the ________________________ task a monkey is presented with a distinctive object (the sample object), under which it finds food. Then, after a specified delay, the monkey is presented with two test objects: a sample object and an unfamiliar object. The monkey must select an unfamiliar object to receive a food reward.
A. delayed nonmatching-to-sample
B. nondelayed matching-to-sample
C. delayed matching-to-sample
D. repetition priming

A

a

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17
Q

_____ developed the version of the delayed nonmatching-to-sample test for rats that most closely resembles the version for monkeys.
A. Squire
B. Mumby
C. Nadel
D. Barnes

A

b

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18
Q

Almost all studies of hippocampal lesions in monkeys and humans entail damage to large portions of the ____________ in addition to the hippocampus.
A. basal forebrain
B. rhinal cortex
C. mumby nuclei
D. mediodorsal nuclei of the thalamus

A

b

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19
Q

The results of delayed nonmatching-to-sample tests indicate that combined bilateral lesions of the hippocampus, amygdala, and medial temporal cortex have similar effects on memory in humans, monkeys, and rats – namely:
A. major deficits at all but the shortest retention intervals.
B. minor deficits but only at the shortest retention intervals.
C. major deficits at all but the longest retention intervals.
D. minor deficits but only at the longest retention intervals.

A

a

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20
Q

Selective bilateral removal of the hippocampus without damaging adjacent medial temporal lobe structures produces ____________ on the delayed nonmatching-to-sample test and other tests of object recognition.
A. no deficits
B. improvements
C. severe deficits
D. modest deficits

A

d

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21
Q

Place and grid cells are found in the _____ and attest to the structure’s role in _____ processing.
A. hippocampus; emotional
B. hippocampus; spatial
C. amygdala; spatial
D. amygdala; emotional

A

b

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22
Q

In the ____________________ water maze, intact rats placed at various locations in a circular pool of murky water rapidly learn to swim to a stationary platform hidden just below the surface.
A. Morris
B. Mumby
C. murky
D. radial

A

a

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23
Q

________________ cells are entorhinal neurons that each have an extensive array of evenly spaced place fields, producing a pattern reminiscent of graph paper.
A. Graph
B. Place
C. Grid
D. Morris

A

c

24
Q

Neurons in the medial temporal lobes that are highly selective in terms of their responses to classes of test objects or individuals are known as:
A. Lisa Kudrow neurons.
B. Whoopi Goldberg neurons.
C. concept cells.
D. Hebb cells.

A

c

25
Q

The optogenetic identification of an engram cell typically involves two stages in sequence: first a _________________ stage and then a ______________ stage.
A. encoding; recall
B. tagging; manipulate
C. manipulate; tagging
D. storage; recall

A

b

26
Q

Naya, Yoshida, and Miyashita (2001) recorded the responses of neurons while monkeys learned the relation between pairs of visual images. When the monkeys were required to recall that pair, activity was recorded in ____________ neurons before ____________ neurons.
A. inferotemporal; hippocampal
B. inferotemporal; perirhinal
C. perirhinal; inferotemporal
D. hippocampal; inferotemporal

A

c

27
Q

Rats with ______________ lesions, unlike intact rats, do not respond with fear to a neutral stimulus that has previously been followed by an electric foot shock.
A. Amygdalar
B. hippocampal
C. striatal
D. inferotemporal

A

a

28
Q

Involvement of the ______________ during memory formation may account for the fact that emotion-provoking events are remembered better than neutral events.
A. inferotemporal cortex
B. amygdala
C. perirhinal cortex
D. cerebellum

A

b

29
Q

Patients with large prefrontal lesions often have difficulty performing tasks that involve:
A. a series of responses.
B. emotions.
C. sensorimotor learning.
D. visual stimuli.

A

a

30
Q

he role of the ____________________ in the Pavlovian conditioning of the eye-blink response of rabbits has been intensively investigated.
A. cerebellum
B. striatum
C. inferotemporal cortex
D. amygdala

A

a

31
Q

Bliss and Lømø showed that there is a facilitation of synaptic transmission following high-frequency electrical stimulation applied to presynaptic neurons. This phenomenon has been termed:
A. high-frequency facilitation.
B. long-term potentiation.
C. presynaptic facilitation.
D. long-term modification.

A

b

32
Q

The fact that it ______ is one feature of long-term potentiation (LTP) that Hebb argued was an important property of learning and memory.
A. occurs in the hippocampus
B. can last for a long time
C. develops only if the firing of the presynaptic neuron is preceded by the firing of the postsynaptic neuron
D. occurs in the amygdala

A

b

33
Q

Even if glutamate binds to it, an NMDA receptor does not respond maximally unless ___________.
A. the postsynaptic neuron already is partially depolarized.
B. the glutamate is sufficiently excitatory.
C. its calcium channels are inhibited.
D. the postsynaptic neuron already is partially hyperpolarized.

A

a

34
Q

The reason that the effects of long-term potentiation (LTP) at one synapse on a neuron do not spread to nearby synapses on the same neuron is likely because of:
A. calcium influx.
B. dendritic spines.
C. the NMDA receptor.
D. glutamate inhibitor protein.

A

b

35
Q

________________ refers to the modulation of the ability to induce LTP at particular synapses.
A. Neuroplasticity
B. Metaplasticity
C. Long-term depression (LTD)
D. Synaptic facilitation

A

b

36
Q

In a study of infantile amnesia, children were shown a series of photographs of preschool-aged children, some of whom had been their preschool classmates. Whether they explicitly remembered a former classmate or not, they consistently displayed a _______________ to the photographs of their former classmates.
A. weak skin conductance response
B. large hippocampal fMRI signal
C. large general fMRI signal
D. large skin conductance response

A

d

37
Q

_________________ are substances (drugs, supplements, herbal extracts, etc.) that are thought to improve memory.
A. Nootropics
B. IQ pills
C. Intelligence drugs
D. NMDA receptor agonists

A

a

38
Q

Although smart pills are often marketed to healthy adults, the most relevant research has been done on:
A. juvenile nonhumans.
B. nonhumans or humans with memory difficulties.
C. nonhumans with exceptional memory.
D. H.M.

A

b

39
Q

An advertisement touts a new nootropic supplement, or smart pill, promising to turbocharge one’s memory and propel academic, career, and relationship success. Which statement is LEAST likely true of any research evaluating the new supplement?
A. It has few participants.
B. It found only small effects.
C. It lacks rigorous controls.
D. It was performed on healthy humans with normal memory function.

A

d

40
Q

The presentation of R.M.’s posttraumatic amnesia was ironic because:
A. R.M. had treated H.M. for epilepsy.
B. H.M. also had a brain injury from skiing.
C. H.M. also was a biopsychologist.
D. one of the few things that R.M. could remember during his confusion was the case of H.M.

A

d

41
Q

H.M.’s digit span performance was:
A. within the normal range.
B. lower than 90 percent of persons tested.
C. better than 90 percent of persons tested.
D. difficult to assess due to fluctuations in his performance.

A

a

42
Q

Semantic memories are ___________ memories.
A. short-term
B. episodic
C. implicit
D. explicit

A

d

43
Q

Transient global amnesia is defined by its:
A. clear link to significant traumatic brain injury.
B. sudden onset in the absence of any obvious cause
C. often imperceptible occurrence.
D. unusually long duration.

A

b

44
Q

During the early stages of Korsakoff’s syndrome, _________________ amnesia for _____ episodic memory is the MOST prominent symptom.
A. retrograde; implicit
B. retrograde; explicit
C. anterograde; implicit
D. anterograde; explicit

A

d

45
Q

Posttraumatic amnesia can be induced by:
A. repetition priming.
B. electroconvulsive shock.
C. thiamine.
D. alcohol.

A

b

46
Q

____________ is/are produced by electroconvulsive shock in humans and other animals.
A. Place cell depletion
B. Temporal gradients of retrograde amnesia
C. Spatial gradients of anterograde amnesia
D. Psychoses

A

b

47
Q

Temporal gradients of retrograde amnesia provide evidence for:
A. microstrokes.
B. the transfer of memory.
C. consolidation.
D. degeneration.

A

c

48
Q

Large deficits in delayed nonmatching-to-sample are caused by bilateral lesions to the:
A. hippocampus.
B. medial temporal lobe cortex.
C. corpus callosum.
D. amygdala.

A

b

49
Q

Grid cells are:
A. entorhinal cortex neurons.
B. hippocampal neurons.
C. place cells.
D. Schwann cells.

A

a

50
Q

The hippocampus plays a major role in memory for:
A. spatial location.
B. emotional significance.
C. faces.
D. words.

A

a

51
Q

The ____________ is thought to play a role in memory for the emotional significance of experiences.
A. hippocampus
B. cerebellum
C. amygdala
D. inferotemporal cortex

A

c

52
Q

Which test involves the use of a hidden platform?
A. radial arm maze
B. delayed nonmatching-to-sample test
C. repetition priming test
D. Morris water maze

A

d

53
Q

The induction of LTP at synapses with NMDA receptors depends on the influx of:
A. sodium ions into the postsynaptic neuron.
B. potassium ions into the presynaptic neuron.
C. calcium ions into the presynaptic neuron.
D. calcium ions into the postsynaptic neuron.

A

d

54
Q

The flip side of long-term potentiation (LTP) is known as ____ and occurs in response to prolonged low-frequency stimulation of presynaptic neurons.
A. metaplasticity
B. long-term depression (LTD)
C. low-frequency potentiation (LFP)
D. high-frequency potentiation (HFP)

A

b

55
Q

The research of Newcombe and her colleagues (e.g., Newcombe, 2000) reveals that infantile amnesia is:
A. a myth, as both explicit and implicit memory are preserved for events during infancy and early childhood.
B. a misnomer, as implicit memory for events during infancy and early childhood are preserved even in the absence of explicit memories.
C. a misnomer, as explicit memory for events during infancy and early childhood are preserved despite the absence of implicit memories.
D. pervasive, as neither explicit nor implicit memory is preserved for events during infancy and early childhood.

A

b