Chapter 10 (Exam 3) Flashcards
What did Frederick Griffith discover in relation to DNA?
A “transforming principle” was responsible for hereditary material being passed through generations
Who discovered a “transforming principle” being responsible for hereditary material being passed through generations?
Frederick Griffith
What did Oswald Avery discover in relation to DNA?
Repeated Frederick Griffith’s work and asserted that DNA was the hereditary material
Who repeated Frederick Griffith’s work, asserting that DNA was the gereditary material?
Oswald Avery
Who discovered that DNA was the genetic material?
Max Delbruck, Alfred Hershey, Martha Chase, et al.
What did Max Delbruck, Alfred Hershey and Martha Chase discover in relation to DNA?
DNA was the hereditary material not, proteins
Who discovered DNA’s structure?
Francis Crick and James Watson
What did Francis Crick and James Watson discover in relation to DNA?
DNA’s structure
Who provided the information necessary to discover DNA’s structure?
Rosalind Franklin and Maurice Wilkins
How did Rosalind Franklin and Maurice Wilkins help discover DNA’s structue?
provide x-ray diffraction studies of DNA
DNA strands are ___.
anti-parallel
What does it mean for DNA strands to be anti-parallel?
5’ -> 3’ and 3’ -> 5’
What is the backbone of DNA?
Phosphodiester bonds
What do phosphodiester bonds do for DNA?
backbone that holds nucleotides together
What forms the steps of the ladder shape of DNA?
nitrogenous bases held together by hydrogen bonds
What holds the nitrogenous bases together in DNA?
hydrogen bonds
Nitrogenous bases are the ___ of the DNA ladder.
steps
What do hydrogen bonds do in DNA?
hold nitrogenous bases together
What are the 4 nitrogen bases?
Adenine, Thymine, Guanine, Cytosine
Adenine pairs with ___.
Thymine
Thymine pairs with ___.
Adenine
Guanine pairs with ___.
Cytosine
Cytosine pairs with ___.
Guanine
Why is DNA replication considered Semi-Concertive?
half the strands are newly-synthesized and the other half are templates
What is the first step of DNA replication?
unwinding the DNA
What is the second step of DNA replication?
nucleotide additions
What is the third step of DNA replication?
sealing the gaps
What enzyme unwinds the DNA strands during replication?
DNA Helicase
What does the DNA Helicase enzyme do during DNA replication?
unwinds the DNA strands
What enzyme adds new bases to the exposed bases during DNA replication?
DNA Polymerase