Ch.20 bonus Quiz Flashcards
Chemotherapy
use of drugs to treat disease
Antimicrobial drugs
interfere with the growth of microbes within a host. Like penicillin.
Antibiotic
substance produced by a microbe that in small amount inhibits another microbe
Selective Toxicity
Killing harmful microbes without damaging the host
Broad Spectrum
Affect Gram + and gram - bacteria
Narrow Spectrum
Range of microbes is impacted , like Pencillin G impacts mostly gram + and some gram negative
Superinfection
growth of a pathogen that has developed resistance or growth of opportunistic pathogen
Bactericidal
Kills bacteria
Bacteriostatic
Prevents microbes from growing
how do antibiotics kills
they target the cell wall during synthesis , and prevent cross-bridging of amino acids in the peptidoglycan
Another way antibiotics kill
they interrupt protein synthesis like stopping peptide bond formation
Disk diffusion method
disk of antibiotics that are used to determine how useful a drug is. The zone of inhibiting if measured. You can’t tell if it kills bacteria or is bacterial static . IMpacts growth but don’t know HOW
How does antibiotic resistance occur
mutations and resistance genes transferred via plasmids . Misuse. animal feed, differring from prescription , weakened antibiotics
how do antibiotic bacteria fight antibiotics
they can block entry, deactivate their enzymes, alter their target molecule, and push out the the antibiotic
Synergism and Antagonism
when 2 combine work better togther than seperate and the opposite