ch 6 Flashcards
promoters
specific DNA sequences
activators
transcription factors
bind DNA and activate transcription
what are transcription factors
proteins that help control the process of transcription
mechanisms of activators
recruits RNA polymerase
loosening chromatin
recruiting coactivators
coactivators
other proteins that help initiate transcription
they recruit RNA polymerase
repressors
proteins that induce transcription
mechanisms of repressors
prevent activators from binding
closing chromatin
recruits corepressors
corepressors
proteins that help prevent transcription
enhancers
DNA regions FURTHER AWAY from transcription start site
brought near promoter using DNA looping
T/F: there are multiple enhancers per gene
true
sillencers
inhibitory
distant DNA sites that inhibit transcription
recruit repressive transcription factors
heterochromatin
tightly compacted chromatin
euchromatin
loosely compacted chromatin
what controls chromatin compaction
chemical modifications of DNA bases
chemical modifications of some histones
DNA methylation
methyl groups added to Cytosine
happens mostly at gene promoter
reduces expression of gene region
T/F: methyl groups are nonpolar and hydrophobic
true!!!
demethylase
enzymes that remove methyl groups
reactivates gene region
writers
enzymes that add methyl groups to DNA
readers
proteins that binds to histones and influences transcription
erasers
proteins that remove histone modifications
what are the two main RNA categories
messenger RNAs
noncoding RNAs
microRNAs
small RNAs that regulate translation
bind to mRNA and prevent genes from being translated into proteins
RISC
RNA-induced silencing complex
recruits proteins to degrade mRNA or stop translation from starting
T/F: miRNA is complementary to the target mRNA
true