ch 6 Flashcards

1
Q

promoters

A

specific DNA sequences

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2
Q

activators

A

transcription factors
bind DNA and activate transcription

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3
Q

what are transcription factors

A

proteins that help control the process of transcription

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4
Q

mechanisms of activators

A

recruits RNA polymerase
loosening chromatin
recruiting coactivators

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5
Q

coactivators

A

other proteins that help initiate transcription

they recruit RNA polymerase

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6
Q

repressors

A

proteins that induce transcription

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7
Q

mechanisms of repressors

A

prevent activators from binding
closing chromatin
recruits corepressors

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8
Q

corepressors

A

proteins that help prevent transcription

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9
Q

enhancers

A

DNA regions FURTHER AWAY from transcription start site

brought near promoter using DNA looping

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10
Q

T/F: there are multiple enhancers per gene

A

true

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11
Q

sillencers

A

inhibitory
distant DNA sites that inhibit transcription

recruit repressive transcription factors

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12
Q

heterochromatin

A

tightly compacted chromatin

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13
Q

euchromatin

A

loosely compacted chromatin

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14
Q

what controls chromatin compaction

A

chemical modifications of DNA bases
chemical modifications of some histones

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15
Q

DNA methylation

A

methyl groups added to Cytosine
happens mostly at gene promoter

reduces expression of gene region

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16
Q

T/F: methyl groups are nonpolar and hydrophobic

17
Q

demethylase

A

enzymes that remove methyl groups
reactivates gene region

18
Q

writers

A

enzymes that add methyl groups to DNA

19
Q

readers

A

proteins that binds to histones and influences transcription

20
Q

erasers

A

proteins that remove histone modifications

21
Q

what are the two main RNA categories

A

messenger RNAs
noncoding RNAs

22
Q

microRNAs

A

small RNAs that regulate translation
bind to mRNA and prevent genes from being translated into proteins

23
Q

RISC

A

RNA-induced silencing complex

recruits proteins to degrade mRNA or stop translation from starting

24
Q

T/F: miRNA is complementary to the target mRNA

25
lncRNA
long noncoding RNA more than 200 nucleotides long diverse functions serves as macromolecular scaffold bind DNA based on complementary base pairing
26
macromolecular scaffold
organize proteins around itself to make a complex
27
miRNA sponging
lncRNAs contain miRNA binding site prevents miRNA from binding to mRNA influences translation of those mRNAs
28
transposons
jumping genes genes that move locations in genome two types -DNA transposons -retrotransposons
29
DNA transposons
cut and paste DNA cut out and placed elsewhere in genome
30
retrotransposons
copy and paste transcribed into RNA RNA is reverse transcribed into DNA DNA inserted into other DNA regions