ch 26: antibacterials Flashcards
what does MEDICATE stand for?
Monitor superinfection
Evaluate renal function
Diarrhea; take with yogurt
Inform provider if taking other medications
Culture prior to initial dose
Ask about allergies
Evaluate temperature, WBCs, and blood culture
what does GIANT stand for? what drugs does it go with?
GI upset Increase glucose levels Anaphylaxis; alcohol may cause vomiting Nephrotoxicity Thrombocytopenia
Cephalosporins
what does GIRL stand for? what drugs does it go with?
GI upset
Increases glucose levels
Reduced activity with antacids
Liver function test
Macrolides
what does SULFA stand for? what drugs does it go with?
Sunlight sensitivity UE rash/renal toxicity Look for urine output and fever Fluid galore (2000 mL/day) Anemia/anorexia
Sulfonamides
what does STOP stand for? what drugs does it go with?
Sunlight sensitivity
Take with a full glass of water
O Don’t take with antacid
Put into an empty stomach
Tetracyclines
what class is erythromycin? where is it absorbed?
macrolides
intestines
what drug class is levofloxacin in? what are the adverse reactions?
quinolones
steven johnson’s, seizures, and pseudomembranous colitis
what is the MOA of beta lactam antibiotics?
- beta lactam bind to penicillin binding proteins
- PBP can’t bind polypeptide chains
- bacteria can’t make cell wall
- bacteria is lysed
what causes an increased effects with penicillins? decreased effects?
- tetracyclines and erythromycin
- aspirin
what causes an increased effect with macrolides?
warfarin, theophylline, and carbomazepine
what can vancomycin cause?
red man’s syndrome, steven johnson’s, nephrotoxicity, ototoxicity
which drug class should you make sure to educate patients to take at least 2000 mL of water a day with?
sulfonamides
